The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …

Adrenocortical carcinoma (ACC) is a highly malignant infrequent tumor with a dismal
prognosis. microRNAs (miRNAs, miRs) are crucial in post-transcriptional gene expression …

Polyphenols are naturally occurring compounds found in abundance in fruits and
vegetables. Their health-promoting properties and their use in the prevention and treatment …

The most known effects of endogenous Cushing's syndrome are the phenotypic changes
and metabolic consequences. However, hypercortisolism can exert important effects on …

Etoposide (ETO) has been used in treating adrenocortical tumor (ACT) cells. Our previous
study showed that ETO inhibits ACT cell growth. In the present study, we show that ETO …

Adrenocortical carcinoma (ACC) is a rare malignancy characterized by aggressive biology
and potential endocrine activity. Surgery can offer cure for localized disease but more than …

A relevant issue on the treatment of adrenocortical carcinoma (ACC) concerns the optimal
duration of adjuvant mitotane treatment. We tried to address this question, assessing …

The design of molecularly imprinted polymers (MIPs) for the specific binding of hydrophobic
molecules (mitotane) was investigated by considering monomers and cross-linking agents …

Cancer is the third leading cause of premature death in sub-Saharan Africa. Cervical cancer
has the highest number of incidences in sub-Saharan Africa due to high HIV prevalence …

Adjuvant and neoadjuvant chemotherapy in the treatment of adrenocortical carcinoma
(ACC) is limited by few existing trials, most of which are retrospective. The drug mitotane has …