The serotonin 5-HT2A receptor is the major target of psychedelic drugs such as lysergic acid
diethylamide (LSD), mescaline, and psilocybin. Serotonergic psychedelics induce profound …

Time is a fundamental dimension of our perception of the world and is therefore of critical
importance to the organization of human behavior. A corpus of work—including recent …

We show that simple assumptions about neural processing lead to a model of interval timing
as a temporal integration process, in which a noisy firing-rate representation of time rises …

Human and mouse subjects tried to anticipate at which of 2 locations a reward would
appear. On a randomly scheduled fraction of the trials, it appeared with a short latency at …

Reinforcement learning (RL) models have been influential in understanding many aspects
of basal ganglia function, from reward prediction to action selection. Time plays an important …

Healthy volunteers were tested on 7-s and 17-s peak-interval timing procedures following d-
amphetamine (20mg—oral), haloperidol (2mg—oral), and placebo treatments in order to …

A number of lines of evidence implicate dopamine in timing [Rammsayer, TH
Neuropharmacological approaches to human timing. In S. Grondin (Ed.), Psychology of time …

Rationale The five-choice serial reaction time task (5-CSRTT) is regularly used to study
attention and impulsivity. In the 5-CSRTT, rodents initiate a trial, then after an inter-trial …

In many species, interval timing behavior is accurate—appropriate estimated durations—
and scalar—errors vary linearly with estimated durations. Whereas accuracy has been …

Highlights•Accuracy and precision are important features of interval timing.•DA AGO/ANT
mainly affect interval timing accuracy by altering the clock speed.•Striatal DRD1 or DRD2 …