Antimicrobial agents, especially antibacterial agents, are used throughout the world, across
a diverse array of extensive and intensive livestock production systems, to protect the health …

This review provides a tutorial for individuals interested in quantitative veterinary
pharmacology and toxicology and offers a basis for establishing guidelines for …

Aim: To develop a comprehensive computational framework to simulate tissue distribution of
gold nanoparticles (AuNP) across several species. Materials & methods: This framework …

Predictions from physiologically based toxicokinetic (PBTK) models can help inform human
health risk assessment for potentially toxic chemicals in the environment. Bisphenol S (BPS) …

Background We hypothesize that in patients with suspected coronary artery disease (CAD),
lower values of the ratio of total epicardial coronary arterial lumen volume to left ventricular …

In today's pharmaceutical research and development, physiologically-based
pharmacokinetic (PBPK) modeling plays an important role in the design, evaluation and …

Objectives Neuropathic pain (NP) represents a broad scope of various pathological
ramifications of the nervous system. Remimazolam is a proved sedative in treating …

Penicillin G is a widely used antimicrobial in food-producing animals, and one of the most
predominant drug residues in animal-derived food products. Due to reduced sensitivity of …

Drug approval processes require extensive testing and have recently put more emphasis on
understanding mechanistic drug action in the body including toxicity and safety. 1 …

Physiologically based pharmacokinetic (PBPK) models for chemicals in food animals are a
useful tool in estimating chemical tissue residues and withdrawal intervals. Physiological …