Fibronectin: molecular structure, fibrillar structure and mechanochemical signaling
CJ Dalton, CA Lemmon - Cells, 2021 - mdpi.com
The extracellular matrix (ECM) plays a key role as both structural scaffold and regulator of
cell signal transduction in tissues. In times of ECM assembly and turnover, cells upregulate …
cell signal transduction in tissues. In times of ECM assembly and turnover, cells upregulate …
Unraveling the mechanobiology of extracellular matrix
V Vogel - Annual review of physiology, 2018 - annualreviews.org
Cells need to be anchored to extracellular matrix (ECM) to survive, yet the role of ECM in
guiding developmental processes, tissue homeostasis, and aging has long been …
guiding developmental processes, tissue homeostasis, and aging has long been …
Feeling things out: bidirectional signaling of the cell–ECM interface, implications in the mechanobiology of cell spreading, migration, proliferation, and differentiation
Biophysical cues stemming from the extracellular environment are rapidly transduced into
discernible chemical messages (mechanotransduction) that direct cellular activities–placing …
discernible chemical messages (mechanotransduction) that direct cellular activities–placing …
The Yin-Yang of rigidity sensing: how forces and mechanical properties regulate the cellular response to materials
According to the Chinese yin-yang concept, seemingly opposing forces give rise and
respond to each other. Opposing forces, whether passive or active, are also at work when …
respond to each other. Opposing forces, whether passive or active, are also at work when …
Molecular architecture of native fibronectin fibrils
Fibronectin fibrils within the extracellular matrix play central roles in physiological and
pathological processes, yet many structural details about their hierarchical and molecular …
pathological processes, yet many structural details about their hierarchical and molecular …
[HTML][HTML] Transglutaminase 2 has higher affinity for relaxed than for stretched fibronectin fibers
Abstract Transglutaminase 2 (TG2) plays a vital role in stabilizing extracellular matrix (ECM)
proteins through enzymatic crosslinking during tissue growth, repair, and inflammation. TG2 …
proteins through enzymatic crosslinking during tissue growth, repair, and inflammation. TG2 …
[HTML][HTML] Simple, admissible, and accurate approximants of the inverse Langevin and Brillouin functions, relevant for strong polymer deformations and flows
M Kroeger - Journal of Non-Newtonian Fluid Mechanics, 2015 - Elsevier
Approximants to the inverse Langevin and Brillouin functions appear in diverse contexts
such as polymer science, molecular dynamics simulations, turbulence modeling …
such as polymer science, molecular dynamics simulations, turbulence modeling …
Regulation of the innate immune response by fibronectin: synergism between the III-1 and EDA domains
R Kelsh, R You, C Horzempa, M Zheng… - PloS one, 2014 - journals.plos.org
Fibronectin is a critical component of the extracellular matrix and alterations to its structure
will influence cellular behavior. Matrix fibronectin is subjected to both mechanical and …
will influence cellular behavior. Matrix fibronectin is subjected to both mechanical and …
Soft-mechanochemistry: mechanochemistry inspired by nature
Cells and bacteria use mechanotransduction processes to transform a mechanical force into
a chemical/biochemical response. The area of chemistry where chemical reactions are …
a chemical/biochemical response. The area of chemistry where chemical reactions are …
Regulation of cell adhesion and migration by cell-derived matrices
Three-dimensional in vitro extracellular matrix models provide a physiological alternative to
regular two-dimensional cell culture, though they lack the full diversity of molecular …
regular two-dimensional cell culture, though they lack the full diversity of molecular …