Pneumonia is an infection of the lower airways (distal bronchi and alveoli) caused by both
viruses and bacteria. Community-acquired pneumonia (CAP) specifically refers to clinical …

Background The clinical and economic outcomes associated with pediatric antimicrobial
stewardship programs (ASPs) and other supplemental antimicrobial stewardship (AS) …

Antibiotic overuse contributes to antibiotic resistance, which is a threat to public health.
Antibiotic stewardship is a practice dedicated to prescribing antibiotics only when necessary …

The prospect of an 'antimicrobial perfect storm'in the coming decades through the
emergence and proliferation of multi-resistant organisms has become an urgent public …

Background: Prolonged or unnecessary antibiotic use is associated with adverse outcomes
in neonates. Our objectives were to quantify all antibiotic use in a Level-III neonatal intensive …

BACKGROUND AND OBJECTIVE: Single-center evaluations of pediatric antimicrobial
stewardship programs (ASPs) suggest that ASPs are effective in reducing and improving …

Standard metrics for antimicrobial use consider volume but not spectrum of antimicrobial
prescribing. We developed an antibiotic spectrum index (ASI) to classify commonly used …

Abstract Background Studies estimate that 30%–50% of antibiotics prescribed for
hospitalized patients are inappropriate, but pediatric data are limited. Characterization of …

Background National guidelines recommend 10 days of antibiotics for children with
community-acquired pneumonia (CAP), acknowledging that the outcomes of children …

The incidence of infections caused by multidrug-resistant (MDR) Gram-negative bacilli
pathogens, affecting humans in hospitals, outpatient health care facilities, and community …