Applicability of in vitro methods in evaluating the biotransformation of polycyclic aromatic hydrocarbons (PAHs) in fish: Advances and challenges

ME Franco, R Lavado - Science of The Total Environment, 2019 - Elsevier
The biotransformation of polycyclic aromatic hydrocarbons (PAHs) and the biochemical
mechanisms involved in such process continue to be intensively studied in the fields of …

Romanian Danube River hydrocarbon pollution in 2011–2021

C Radu, VM Manoiu, K Kubiak-Wójcicka, E Avram… - Water, 2022 - mdpi.com
This review paper aims to analyze studies conducted over recent years (2011–2021) on
hydrocarbon pollution in the Danube's Romanian sector. This involves looking at three main …

[HTML][HTML] Comparative toxicity of conventional versus compostable plastic consumer products: An in-vitro assessment

T Wang, M Hosseinzadeh, A Cuccagna… - Journal of hazardous …, 2023 - Elsevier
This study investigates the toxicity of methanolic extracts obtained from compostable plastics
(BPs) and conventional plastics (both virgin and recycled). Additionally, it explores the …

Sources and metal pollution of sediments from a coastal area of the central western adriatic sea (Southern Marche region, Italy)

F Spagnoli, R De Marco, E Dinelli, E Frapiccini… - Applied Sciences, 2021 - mdpi.com
Sediments represent a critical compartment of marine coastal ecosystems due to the toxic
and long-lasting effects of the contaminants buried therein. Here, we investigated the …

Substituted Two- to Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a

R Lille-Langøy, KB Jørgensen, A Goksøyr… - … science & technology, 2021 - ACS Publications
Polycyclic aromatic hydrocarbons (PAHs) are among the most toxic and bioavailable
components found in petroleum and represent a high risk to aquatic organisms. The aryl …

Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro

H Routti, R Lille-Langøy, MK Berg, T Fink… - … science & technology, 2016 - ACS Publications
We studied interactions between polar bear peroxisome proliferator-activated receptor
gamma (pbPPARG) and selected compounds using a luciferase reporter assay and …

Dysregulation of lipid metabolism in PLHC-1 and ZFL cells exposed to tributyltin an all-trans retinoic acid

A Marqueño, C Flores, M Casado, C Porte - Aquatic Toxicology, 2021 - Elsevier
There is increasing awareness that exposure to endocrine disrupters interferes with lipid
homeostasis in vertebrates, including fish. Many of these compounds exert their action by …

Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a

L Aranguren-Abadía, R Lille-Langøy… - … science & technology, 2019 - ACS Publications
The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that mediates
the toxicity of halogenated and polycyclic aromatic hydrocarbons in vertebrates. Atlantic cod …

Interaction of Bisphenol A and Its Analogs with Estrogen and Androgen Receptor from Atlantic Cod (Gadus morhua)

SØ Gokso̷yr, F Yadetie, CT Johansen… - Environmental …, 2024 - ACS Publications
The widespread use of bisphenol A (BPA) in polycarbonate plastics and epoxy resins has
made it a prevalent environmental pollutant in aquatic ecosystems. BPA poses a significant …

Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays

M Blanco, E Pérez-Albaladejo, B Piña… - Science of the total …, 2018 - Elsevier
A battery of cell-based bioassays, including PLHC-1 cells, zebrafish-Pxr-transfected COS-7
cells and estrogen receptor-recombinant yeast assay (ER-RYA), were applied to detect the …