[HTML][HTML] Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome
BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
[HTML][HTML] Oxidative stress and hyper-inflammation as major drivers of severe COVID-19 and long COVID: implications for the benefit of high-dose intravenous vitamin C
C Vollbracht, K Kraft - Frontiers in Pharmacology, 2022 - frontiersin.org
Oxidative stress is a pivotal point in the pathophysiology of COVID-19 and presumably also
in Long-COVID. Inflammation and oxidative stress are mutually reinforcing each other, thus …
in Long-COVID. Inflammation and oxidative stress are mutually reinforcing each other, thus …
[HTML][HTML] Pilot trial of high-dose vitamin C in critically ill COVID-19 patients
J Zhang, X Rao, Y Li, Y Zhu, F Liu, G Guo, G Luo… - Annals of intensive …, 2021 - Springer
Background Few specific medications have been proven effective for the treatment of
patients with severe coronavirus disease 2019 (COVID-19). Here, we tested whether high …
patients with severe coronavirus disease 2019 (COVID-19). Here, we tested whether high …
[HTML][HTML] The emerging role of vitamin C in the prevention and treatment of COVID-19
AC Carr, S Rowe - Nutrients, 2020 - mdpi.com
Investigation into the role of vitamin C in the prevention and treatment of pneumonia and
sepsis has been underway for many decades. This research has laid a strong foundation for …
sepsis has been underway for many decades. This research has laid a strong foundation for …
Deficiency of antioxidants and increased oxidative stress in COVID-19 patients: A cross-sectional comparative study in Jigawa, Northwestern Nigeria
Y Muhammad, YA Kani, S Iliya… - SAGE open …, 2021 - journals.sagepub.com
Introduction: The COVID-19 is a pandemic caused by SARS-CoV-2 which has infected over
74 million people, killing more than 1,600,000 million people around the world as of 17th …
74 million people, killing more than 1,600,000 million people around the world as of 17th …
[HTML][HTML] Serum levels of vitamin C and vitamin D in a cohort of critically ill COVID-19 patients of a North American community hospital intensive care unit in May 2020 …
Background The COVID-19 pandemic has placed an enormous and growing burden on the
population and health infrastructure, warranting innovative ways to mitigate risk of …
population and health infrastructure, warranting innovative ways to mitigate risk of …
Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials
Background and aims Vitamin C has been used as an anti-oxidant in various diseases
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …
[HTML][HTML] Oxidative stress status in COVID-19 patients hospitalized in intensive care unit for severe pneumonia. A pilot study
J Pincemail, E Cavalier, C Charlier, JP Cheramy–Bien… - Antioxidants, 2021 - mdpi.com
Background: A key role of oxidative stress has been highlighted in the pathogenesis of
COVID-19. However, little has been said about oxidative stress status (OSS) of COVID-19 …
COVID-19. However, little has been said about oxidative stress status (OSS) of COVID-19 …
[HTML][HTML] Vitamin C—An adjunctive therapy for respiratory infection, sepsis and COVID-19
There are limited proven therapies for COVID-19. Vitamin C's antioxidant, anti-inflammatory
and immunomodulating effects make it a potential therapeutic candidate, both for the …
and immunomodulating effects make it a potential therapeutic candidate, both for the …