Arterial stiffness and hypertension in the elderly

S Laurent, P Boutouyrie - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Hypertension prevalence increases with age. Age and high blood pressure are the two main
determinants of arterial stiffness. In elderly hypertensives, large arteries stiffen and systolic …

Arterial stiffness, atherosclerosis and cardiovascular risk: Pathophysiologic mechanisms and emerging clinical indications

C Palombo, M Kozakova - Vascular pharmacology, 2016 - Elsevier
Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix
of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix …

Expert consensus document on arterial stiffness: methodological issues and clinical applications

S Laurent, J Cockcroft, L Van Bortel… - European heart …, 2006 - academic.oup.com
In recent years, great emphasis has been placed on the role of arterial stiffness in the
development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is …

Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular …

MJ Sarnak, AS Levey, AC Schoolwerth, J Coresh… - Circulation, 2003 - Am Heart Assoc
Chronic kidney disease1 (CKD) is a worldwide public health problem. In the United States,
there is a rising incidence and prevalence of kidney failure, with poor outcomes and high …

Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients

S Laurent, P Boutouyrie, R Asmar, I Gautier… - …, 2001 - Am Heart Assoc
Although various studies reported that pulse pressure, an indirect index of arterial stiffening,
was an independent risk factor for mortality, a direct relationship between arterial stiffness …

Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study

FUS Mattace-Raso, TJM van der Cammen, A Hofman… - Circulation, 2006 - Am Heart Assoc
Background—Arterial stiffness has been associated with the risk of cardiovascular disease
in selected groups of patients. We evaluated whether arterial stiffness is a predictor of …

Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study

P Boutouyrie, AI Tropeano, R Asmar, I Gautier… - …, 2002 - Am Heart Assoc
Arterial stiffness may predict coronary heart disease beyond classic risk factors. In a
longitudinal study, we assessed the predictive value of arterial stiffness on coronary heart …

Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease

J Blacher, AP Guerin, B Pannier, SJ Marchais… - …, 2001 - Am Heart Assoc
To test the predictive values of and independent contributions to cardiovascular and all-
cause mortality of various arterial parameters exploring characteristics of the arterial wall at …

Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults

K Sutton-Tyrrell, SS Najjar, RM Boudreau… - Circulation, 2005 - Am Heart Assoc
Background—Aging results in vascular stiffening and an increase in the velocity of the
pressure wave as it travels down the aorta. Increased aortic pulse wave velocity (aPWV) has …

Association between arterial stiffness and atherosclerosis: the Rotterdam Study

NM Van Popele, DE Grobbee, ML Bots, R Asmar… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Studies of the association between arterial stiffness and
atherosclerosis are contradictory. We studied stiffness of the aorta and the common carotid …