[HTML][HTML] Bigels as drug delivery systems: From their components to their applications

A Martín-Illana, F Notario-Pérez, R Cazorla-Luna… - Drug discovery today, 2022 - Elsevier
Highlights•Bigels are systems that usually result from mixing a hydrogel and an
organogel.•A hydrophilic biopolymer is commonly the structuring agent of the aqueous …

[HTML][HTML] Bigels and multi-component organogels: An overview from rheological perspective

A Shakeel, U Farooq, D Gabriele, AG Marangoni… - Food …, 2021 - Elsevier
Background Polymeric gels, an important class of soft matter systems, are widely used for
commercial applications particularly in food products (ie, saturated fat replacement). The …

Development and characterization of novel bigels based on monoglyceride-beeswax oleogel and high acyl gellan gum hydrogel for lycopene delivery

Q Zhu, J Gao, L Han, K Han, W Wei, T Wu, J Li… - Food Chemistry, 2021 - Elsevier
The aim of present study was to develop novel bigels as a semi-solid vehicle for lycopene
delivery. Bigels were prepared by using the mixture of glycerol monostearate (GMS) …

Physicochemical properties and microstructure of bigels formed with gelatin and κ-carrageenan hydrogels and monoglycerides in olive oil oleogels

K Zampouni, CK Mouzakitis, A Lazaridou… - Food …, 2023 - Elsevier
The preparation and properties of novel edible bigel systems based on olive oil oleogels
structured with 15% monoglycerides and different hydrogels formed with 8, 10 or 12 …

Novel bigels constructed from oleogels and hydrogels with contrary thermal characteristics: Phase inversion and 3D printing applications

Z Chen, F Bian, X Cao, Z Shi, Z Meng - Food Hydrocolloids, 2023 - Elsevier
In this study, bigels systems with semi-solid properties were prepared by using the mixture of
beeswax oleogels and hydroxypropyl methylcellulose (HPMC) hydrogels in different …

Seaweed based sustainable films and composites for food and pharmaceutical applications: A review

HPSA Khalil, CK Saurabh, YY Tye, TK Lai… - … and Sustainable Energy …, 2017 - Elsevier
Various studies have been focused on seaweeds derived polysaccharides based
composites because of its renewability and sustainability for food packaging and …

Spirulina platensis protein nanoparticle-based bigels: Dual stabilization, phase inversion, and 3D printing

J Guo, X Gu, L Du, Z Meng - Food Hydrocolloids, 2023 - Elsevier
Nanoparticle-based bigel is a miscellaneous emulsion system consisting of two immiscible
gels, combining Pickering and bigel mechanism, which resulted in enhanced technological …

Hybrid gels: Influence of oleogel/hydrogel ratio on rheological and textural properties

AJ Martins, P Silva, F Maciel, LM Pastrana… - Food research …, 2019 - Elsevier
Hybrid gels can be used for controlled delivery of bioactives and for textural and rheological
modification of foods. In this regard the hydrogel: oleogel ratio and gel development …

Development and characterization of food-grade bigel system for 3D printing applications: Role of oleogel/hydrogel ratios and emulsifiers

D Xie, H Hu, Q Huang, X Lu - Food Hydrocolloids, 2023 - Elsevier
This study objected to widen the knowledge and applications of bigels by constructing food
bigels for 3D printing. A serious of bigels were developed by incorporating a candelilla wax …

Hydrogels as potential nano-, micro-and macro-scale systems for controlled drug delivery

A Chyzy, M Tomczykowa, ME Plonska-Brzezinska - Materials, 2020 - mdpi.com
This review is an extensive evaluation and essential analysis of the design and formation of
hydrogels (HGs) for drug delivery. We review the fundamental principles of HGs (their …