Better understanding of the role of opportunistic infections at ART initiation and IRIS
pathogenesis will assist in improved strategies for prevention and treatment. The long-term …

Antiretroviral therapy (ART) has represented a major advancement in the care of people
living with HIV (PLWHH), resulting in significant reductions in morbidity and mortality through …

In the antiretroviral therapy (ART) era, serious non-AIDS events (SNAEs) have become the
major causes of morbidity and mortality in HIV-infected persons. Early ART initiation has the …

People living with HIV have a 1.5-to 2-fold increased risk of developing cardiovascular
disease. Despite treatment with highly effective antiretroviral therapy, people living with HIV …

Atherosclerotic vascular disease disproportionately affects persons living with HIV (PLWH)
compared to those without. The reasons for the excess risk include dysregulated immune …

Due to a common mode of transmission through infected human blood, hepatitis C virus
(HCV) and human immunodeficiency virus (HIV) co-infection is relatively prevalent. In …

The diagnosis of active tuberculosis (TB) disease remains a challenge, especially in high-
burden settings. Cytokines and chemokines are important in the pathogenesis of TB. Here …

Contributory factors to HIV-associated neurocognitive disorders (HAND) have been shown
to include age, co-morbid infections, medication toxicity, virological, genetic and vascular …

Cognitive impairment has been well documented in human immunodeficiency virus (HIV)
and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co …

HCV infection has been hypothesized as a contributor of poor CD4+ recovery in patients
living with HIV (PLWHIV). Aim of this study was to evaluate CD4+, CD8+ cells and CD4/CD8 …