Functional role of glycosaminoglycans in decellularized lung extracellular matrix

FE Uhl, F Zhang, RA Pouliot, JJ Uriarte, SR Enes… - Acta biomaterialia, 2020 - Elsevier
Despite progress in use of decellularized lung scaffolds in ex vivo lung bioengineering
schemes, including use of gels and other materials derived from the scaffolds, the detailed …

On the road to bioartificial organs

X Ren, HC Ott - Pflügers Archiv-European Journal of Physiology, 2014 - Springer
Biological organs are highly orchestrated systems with well-coordinated positioning,
grouping, and interaction of different cell types within their specialized extracellular …

Strategies for whole lung tissue engineering

EA Calle, M Ghaedi, S Sundaram… - IEEE Transactions …, 2014 - ieeexplore.ieee.org
Recent work has demonstrated the feasibility of using decellularized lung extracellular
matrix scaffolds to support the engineering of functional lung tissue in vitro. Rendered …

Preparation of decellularized lung matrices for cell culture and protein analysis

FE Uhl, DE Wagner, DJ Weiss - Fibrosis: Methods and Protocols, 2017 - Springer
The limited available treatment options for patients with chronic lung diseases, such as
fibrosis, lead to poor prognosis after diagnosis and short survival rates. An exciting new …

Use of high-rate ventilation results in enhanced recellularization of bioengineered lung scaffolds

MA Ahmadipour, D Taniguchi… - … Engineering Part C …, 2021 - liebertpub.com
While transplantation is a viable treatment option for end-stage lung diseases, this option is
highly constrained by the availability of organs and postoperative complications. A potential …

Perfusion decellularization of discarded human kidneys: a valuable platform for organ regeneration

HC Ott - Transplantation, 2015 - journals.lww.com
In this issue of Transplantation, Peloso and colleagues1 report on the successful application
of perfusion decellularization in discarded human kidneys to generate scaffolds for organ …

[PDF][PDF] Aligned polymer scaffolds in periodontal tissue engineering

D Alotaibi - 2014 - etheses.whiterose.ac.uk
Periodontal disease is characterised by progressive gingival inflammation and degradation
of the periodontal ligament (PDL) and alveolar bone. Recently, a limited number of studies …

Negative pressure and its role in lung re-epithelialization

MA Ahmadipour - 2020 - search.proquest.com
For end-stage lung disease, lung transplantation remains the only treatment.
Transplantation, however, is limited due to the lack of organs. While the generation of new …