[HTML][HTML] TGF-β signaling in the tumor metabolic microenvironment and targeted therapies

X Shi, J Yang, S Deng, H Xu, D Wu, Q Zeng… - Journal of Hematology & …, 2022 - Springer
Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer
progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in …

Recent advances in small-molecule fluorescent probes for diagnosis of cancer cells/tissues

K Wang, C Liu, H Zhu, Y Zhang, M Su, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Cancer has always been covetous to the health of human beings, and countless people die
every year due to cancer. Accurate diagnosis of cancer is an important prerequisite for its …

Lipid droplets in the nervous system

I Ralhan, CL Chang, J Lippincott-Schwartz… - Journal of Cell …, 2021 - rupress.org
Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

[HTML][HTML] Lipid droplets in cancer: guardians of fat in a stressful world

T Petan, E Jarc, M Jusović - Molecules, 2018 - mdpi.com
Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …

Bright near-infrared aggregation-induced emission luminogens with strong two-photon absorption, excellent organelle specificity, and efficient photodynamic therapy …

Z Zheng, T Zhang, H Liu, Y Chen, RTK Kwok, C Ma… - Acs Nano, 2018 - ACS Publications
Far-red and near-infrared (NIR) fluorescent materials possessing the characteristics of
strong two-photon absorption and aggregation-induced emission (AIE) as well as specific …

Ultrabright and fluorogenic probes for multicolor imaging and tracking of lipid droplets in cells and tissues

M Collot, TK Fam, P Ashokkumar… - Journal of the …, 2018 - ACS Publications
Lipid droplets (LDs) are intracellular lipid-rich organelles that regulate the storage of neutral
lipids and were recently found to be involved in many physiological processes, metabolic …

[HTML][HTML] Mitochondria bound to lipid droplets: where mitochondrial dynamics regulate lipid storage and utilization

IY Benador, M Veliova, M Liesa, OS Shirihai - Cell metabolism, 2019 - cell.com
The isolation and biochemical characterization of lipid droplet (LD)-associated mitochondria
revealed the capacity of the cell to produce and maintain distinct mitochondrial populations …

The assembly of lipid droplets and their roles in challenged cells

WM Henne, ML Reese, JM Goodman - The EMBO journal, 2018 - embopress.org
Cytoplasmic lipid droplets are important organelles in nearly every eukaryotic and some
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …

[HTML][HTML] Emerging role of lipid metabolism alterations in Cancer stem cells

M Yi, J Li, S Chen, J Cai, Y Ban, Q Peng, Y Zhou… - Journal of Experimental …, 2018 - Springer
Abstract Background Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …

[HTML][HTML] Lipid metabolism alteration contributes to and maintains the properties of cancer stem cells

H Li, Z Feng, ML He - Theranostics, 2020 - ncbi.nlm.nih.gov
Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …