Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …

Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …

Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …

Adjuvants incorporated in prophylactic and/or therapeutic vaccine formulations impact
vaccine efficacy by enhancing, modulating, and/or prolonging the immune response. In …

Background Chikungunya virus—a mosquito-borne alphavirus—is endemic in Africa and
south and southeast Asia and has recently emerged in the Caribbean. No drugs or vaccines …

The baculovirus expression vector system (BEVS) platform has become an established
manufacturing platform for the production of viral vaccines and gene therapy vectors. Nine …

Beginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to
Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks …

Chikungunya virus (CHIKV) is a re-emergent arthropod-borne virus (arbovirus) that causes a
disease characterized primarily by fever, rash and severe persistent polyarthralgia. In the …

Chikungunya fever (CHIKF) is an acute infectious disease that is mediated by the mosquito-
transmitted chikungunya virus (CHIKV). People infected with CHIKV may experience high …

Arthritogenic alphaviruses are responsible for a dengue-like syndrome associated with
severe debilitating polyarthralgia that can persist for months or years and impact life quality …