Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Disrupted protein folding or decreased protein stability can lead to the accumulation of
(partially) un‐or misfolded proteins, which ultimately cause the formation of protein …

The self-assembly of proteins is an essential process for a variety of cellular functions
including cell respiration, mobility and division. On the other hand, protein or peptide …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by
the loss of motor neurons in the brain and spinal cord. While the exact causes of ALS are still …

In the outer mitochondrial membrane (OMM), the voltage-dependent anion channel 1
(VDAC1) serves as a mitochondrial gatekeeper, controlling the metabolic and energy cross …

Abstract Significance: Reduction/oxidation (redox) balance could be defined as an even
distribution of reduction and oxidation complementary processes and their reaction end …

Heavy metals, including lead (Pb), cadmium (Cd), arsenic (As), cobalt (Co), copper (Cu),
manganese (Mn), zinc (Zn), and others, have a significant impact on the development and …

Impaired mitochondrial function has been proposed as a causative factor in
neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), caused by motor …

Few proteins have come under such intense scrutiny as superoxide dismutase-1 (SOD1).
For almost a century, scientists have dissected its form, function and then later its …

Mesoporous vaterite CaCO 3 crystals are nowadays one of the most popular vectors for
loading of fragile biomolecules like proteins due to biocompatibility, high loading capacity …