G-protein-coupled receptors transmit signals through cascades of cellular signaling
molecules to orchestrate physiological responses. Measuring the time course (kinetics or …

Reactive astrocytes are associated with neuroinflammation and cognitive decline in diverse
neuropathologies; however, the underlying mechanisms are unclear. We used optogenetic …

Tardigrades are microscopic animals that survive desiccation by inducing biostasis. To
survive drying tardigrades rely on intrinsically disordered CAHS proteins, which also …

Understanding the mechanisms underlying amyotrophic lateral sclerosis (ALS) is crucial for
the development of new therapies. Previous studies have demonstrated that mitochondrial …

Retinitis pigmentosa (RP) is a hereditary blinding disease characterized by gradual
photoreceptor death, which lacks a definitive treatment. Here, we demonstrated the effect of …

Background The exact mechanisms underlying neuroinflammation and how they contribute
to amyotrophic lateral sclerosis (ALS) pathogenesis remain unclear. One possibility is the …

A novel electrochemical biosensor was developed to monitor fibroblast cells stress levels for
the first time in situ under external stimuli based on the recognition of superoxide anion …

Hexabromocyclododecane (HBCD), was a widely utilized brominated flame retardant,
commonly found in a wide range of household products. The pervasiveness of HBCD has …