Macroautophagy/autophagy is a homeostatic process with multiple effects on immunity. One
of the pivotal contributions of autophagy in immunity is the cell autonomous control of …

Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …

The surveillance and elimination of fungal pathogens rely heavily on the sentinel behaviour
of phagocytic cells of the innate immune system, especially macrophages and neutrophils …

Neutrophil extracellular traps (NETs) are structures consisting of chromatin and antimicrobial
molecules that are released by neutrophils during a form of regulated cell death called …

Phagocytosis, the regulated uptake of large particles (> 0.5 μm in diameter), is essential for
tissue homeostasis and is also an early, critical component of the innate immune response …

Metastasis accounts for the vast majority of cancer deaths. The unique challenges for
treating metastases include their small size, high multiplicity and dispersion to diverse organ …

The inflammatory nature of atherosclerosis is well established but the agent (s) that incite
inflammation in the artery wall remain largely unknown. Germ-free animals are susceptible …

(Macro) autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …

Recognition of microbial pathogens and dead cells and their phagocytic uptake by
specialized immune cells are essential to maintain host homeostasis. Phagosomes undergo …

Microglia are the resident brain macrophages and they have been traditionally studied as
orchestrators of the brain inflammatory response during infections and disease. In addition …