A history of exploring cancer in context

S Maman, IP Witz - Nature Reviews Cancer, 2018 - nature.com
The concept that progression of cancer is regulated by interactions of cancer cells with their
microenvironment was postulated by Stephen Paget over a century ago. Contemporary …

Endothelial progenitor cells: characterization and role in vascular biology

C Urbich, S Dimmeler - Circulation research, 2004 - Am Heart Assoc
Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial
progenitor cells augments neovascularization of tissue after ischemia and contributes to …

Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling

X Zhang, F Hu, G Li, G Li, X Yang, L Liu, R Zhang… - Cell death & …, 2018 - nature.com
Mesenchymal stem cells (MSCs) have been reported to localize in colorectal carcinomas,
and participate in the formation of the tumor microenvironment. They have recently been …

Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression

EL Spaeth, JL Dembinski, AK Sasser, K Watson… - PloS one, 2009 - journals.plos.org
Background Tumor associated fibroblasts (TAF), are essential for tumor progression
providing both a functional and structural supportive environment. TAF, known as activated …

[HTML][HTML] Current and future options for dental pulp therapy

T Morotomi, A Washio, C Kitamura - Japanese Dental Science Review, 2019 - Elsevier
Dental pulp is a connective tissue and has functions that include initiative, formative,
protective, nutritive, and reparative activities. However, it has relatively low compliance …

Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

K Otsu, S Das, SD Houser, SK Quadri… - Blood, The Journal …, 2009 - ashpublications.org
Mesenchymal stem cells (MSCs), which potentially transdifferentiate into multiple cell types,
are increasingly reported to be beneficial in models of organ system injury. However, the …

Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells

JS Duffield, KM Park, LL Hsiao… - The Journal of …, 2005 - Am Soc Clin Investig
Ischemia causes kidney tubular cell damage and abnormal renal function. The kidney is
capable of morphological restoration of tubules and recovery of function. Recently, it has …

Mesenchymal stem cells enhance growth and metastasis of colon cancer

K Shinagawa, Y Kitadai, M Tanaka… - … journal of cancer, 2010 - Wiley Online Library
Recently, mesenchymal stem cells (MSCs) were reported to migrate to tumor stroma as well
as injured tissue. We examined the role of human MSCs in tumor stroma using an orthotopic …

Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis

IAW Ho, HC Toh, WH Ng, YL Teo, CM Guo, KM Hui… - Stem …, 2013 - academic.oup.com
Tumor tropism of human bone marrow-derived mesenchymal stem cells (MSC) has been
exploited for the delivery of therapeutic genes for anticancer therapy. However, the exact …

Human melanoma cells transplanted into zebrafish proliferate, migrate, produce melanin, form masses and stimulate angiogenesis in zebrafish

M Haldi, C Ton, WL Seng, P McGrath - Angiogenesis, 2006 - Springer
In this research, we optimized parameters for xenotransplanting WM-266-4, a metastatic
melanoma cell line, including zebrafish site and stage for transplantation, number of cells …