Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

M Sartelli, F Catena, FM Abu-Zidan, L Ansaloni… - World journal of …, 2017 - Springer
This paper reports on the consensus conference on the management of intra-abdominal
infections (IAIs) which was held on July 23, 2016, in Dublin, Ireland, as a part of the annual …

Secondary peritonitis and intra-abdominal sepsis: an increasingly global disease in search of better systemic therapies

TW Clements, M Tolonen, CG Ball… - … Journal of Surgery, 2021 - journals.sagepub.com
Secondary peritonitis and intra-abdominal sepsis are a global health problem. The life-
threatening systemic insult that results from intra-abdominal sepsis has been extensively …

The mesentery, systemic inflammation, and Crohn's disease

ED Rivera, JC Coffey, D Walsh… - Inflammatory bowel …, 2019 - academic.oup.com
Initially thought to be a structure that only provided support to the abdominal contents, the
mesentery has now gained special attention in the scientific community. The new approach …

Peritoneal negative pressure therapy prevents multiple organ injury in a chronic porcine sepsis and ischemia/reperfusion model

BD Kubiak, SP Albert, LA Gatto, KP Snyder, KG Maier… - Shock, 2010 - journals.lww.com
Sepsis and hemorrhage can result in injury to multiple organs and is associated with an
extremely high rate of mortality. We hypothesized that peritoneal negative pressure therapy …

Elevation of HO‐1 expression mitigates intestinal ischemia‐reperfusion injury and restores tight junction function in a rat liver transplantation model

X Chi, W Yao, H Xia, Y Jin, X Li, J Cai… - Oxidative medicine and …, 2015 - Wiley Online Library
Aims. This study was aimed at investigating whether elevation of heme oxygenase‐1 (HO‐1)
expression could lead to restoring intestinal tight junction (TJ) function in a rat liver …

Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia

Y Yuan, I Alwis, MCL Wu, Z Kaplan… - Science Translational …, 2017 - science.org
Gut ischemia is common in critically ill patients, promoting thrombosis and inflammation in
distant organs. The mechanisms linking hemodynamic changes in the gut to remote organ …

[HTML][HTML] Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation under high-altitude hypoxic environment

QQ Zhou, DZ Yang, YJ Luo, SZ Li, FY Liu… - World Journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To study whether over-starvation aggravates intestinal mucosal injury and promotes
bacterial and endotoxin translocation in a high-altitude hypoxic environment. METHODS …

Removal of Inflammatory Ascites Is Associated With Dynamic Modification of Local and Systemic Inflammation Along With Prevention of Acute Lung Injury: In Vivo: and …

B Emr, D Sadowsky, N Azhar, LA Gatto, G An… - Shock, 2014 - journals.lww.com
Background: Sepsis-induced inflammation in the gut/peritoneal compartment occurs early in
sepsis and can lead to acute lung injury (ALI). We have suggested that inflammatory ascites …

Toward computational identification of multiscale “tipping points” in acute inflammation and multiple organ failure

G An, G Nieman, Y Vodovotz - Annals of biomedical engineering, 2012 - Springer
Sepsis accounts annually for nearly 10% of total US deaths, costing nearly $17 billion/year.
Sepsis is a manifestation of disordered systemic inflammation. Properly regulated …

A review of metabolic staging in severely injured patients

MA Aller, JI Arias, A Alonso-Poza, J Arias - Scandinavian journal of trauma …, 2010 - Springer
An interpretation of the metabolic response to injury in patients with severe accidental or
surgical trauma is made. In the last century, various authors attributed a meaning to the post …