Role and significance of lytic polysaccharide monooxygenases (LPMOs) in lignocellulose deconstruction

RR Singhania, P Dixit, AK Patel, BS Giri, CH Kuo… - Bioresource …, 2021 - Elsevier
Lytic polysaccharide monooxygenases (LPMOs) emerged a decade ago and have been
described as biomass deconstruction boosters as they play an extremely important role in …

Lytic polysaccharide monooxygenase (LPMO)-derived saccharification of lignocellulosic biomass

M Moon, JP Lee, GW Park, JS Lee, HJ Park… - Bioresource Technology, 2022 - Elsevier
Given that traditional biorefineries have been based on microbial fermentation to produce
useful fuels, materials, and chemicals as metabolites, saccharification is an important step to …

Kinetic insights into the peroxygenase activity of cellulose-active lytic polysaccharide monooxygenases (LPMOs)

R Kont, B Bissaro, VGH Eijsink, P Väljamäe - Nature Communications, 2020 - nature.com
Lytic polysaccharide monooxygenases (LPMOs) are widely distributed in Nature, where they
catalyze the hydroxylation of glycosidic bonds in polysaccharides. Despite the importance of …

The “life-span” of lytic polysaccharide monooxygenases (LPMOs) correlates to the number of turnovers in the reductant peroxidase reaction

S Kuusk, VGH Eijsink, P Väljamäe - Journal of Biological Chemistry, 2023 - ASBMB
Lytic polysaccharide monooxygenases (LPMOs) are monocopper enzymes that degrade the
insoluble crystalline polysaccharides cellulose and chitin. Besides the H 2 O 2 cosubstrate …

Electrochemical monitoring of heterogeneous peroxygenase reactions unravels LPMO kinetics

L Schwaiger, F Csarman, H Chang, O Golten… - ACS …, 2024 - ACS Publications
Biological conversion of plant biomass depends on peroxygenases and peroxidases acting
on insoluble polysaccharides and lignin. Among these are cellulose-and hemicellulose …

Insights into the H2O2‐driven catalytic mechanism of fungal lytic polysaccharide monooxygenases

TM Hedison, E Breslmayr, M Shanmugam… - The FEBS …, 2021 - Wiley Online Library
Fungal lytic polysaccharide monooxygenases (LPMOs) depolymerise crystalline cellulose
and hemicellulose, supporting the utilisation of lignocellulosic biomass as a feedstock for …

Comparison of Six Lytic Polysaccharide Monooxygenases from Thermothielavioides terrestris Shows That Functional Variation Underlies the Multiplicity of LPMO …

M Tõlgo, OA Hegnar, H Østby, A Várnai… - Applied and …, 2022 - Am Soc Microbiol
Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that oxidatively
degrade various polysaccharides. Genes encoding LPMOs in the AA9 family are abundant …

Kinetics of H2O2-driven catalysis by a lytic polysaccharide monooxygenase from the fungus Trichoderma reesei

S Kuusk, P Väljamäe - Journal of Biological Chemistry, 2021 - ASBMB
Owing to their ability to break glycosidic bonds in recalcitrant crystalline polysaccharides
such as cellulose, the catalysis effected by lytic polysaccharide monooxygenases (LPMOs) …

[HTML][HTML] Heterologous expression of lytic polysaccharide monooxygenases (LPMOs)

Y Gaber, B Rashad, R Hussein, M Abdelgawad… - Biotechnology …, 2020 - Elsevier
Lytic polysaccharide monooxygenases (LPMOs) are relatively new enzymes that have been
discovered 10 years ago. LPMOs comprise a diverse group of enzymes which play a pivotal …

On the pH Dependency of the Catalysis by a Lytic Polysaccharide Monooxygenase from the Fungus Trichoderma reesei

S Kuusk, M Lipp, S Mahajan, P Väljamäe - ACS Catalysis, 2024 - ACS Publications
Lytic polysaccharide monooxygenases (LPMOs) catalyze the oxidative cleavage of
glycosidic bonds in industrially important polysaccharides like cellulose. The activity of these …