Humans encounter mycobacterial species due to their ubiquity in different environmental
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …

Myelination of axons in the nervous system of vertebrates enables fast, saltatory impulse
propagation, one of the best-understood concepts in neurophysiology. However, it took a …

Schwann cell dedifferentiation from a myelinating to a progenitor-like cell underlies the
remarkable ability of peripheral nerves to regenerate following injury. However, the …

Tuberculosis, an ancient disease of mankind, remains one of the major infectious causes of
human death. We examine newly discovered facets of tuberculosis pathogenesis and …

Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively
in the isthmus of the glands, from where cells migrate bidirectionally toward pit and base …

The intrinsic neural networks of the gastrointestinal tract are derived from dedicated neural
crest progenitors that colonize the gut during embryogenesis and give rise to enteric …

Nerves are a component of the tumor microenvironment contributing to cancer progression,
but the role of cells from nerves in facilitating cancer invasion remains poorly understood …

Despite significant improvements in leprosy (Hansen's disease) treatment and outlook for
patients since the introduction of multidrug therapy (MDT) 3 decades ago, the global …

Persisters are a small fraction of quiescent bacterial cells that survive lethal antibiotics or
stresses but can regrow under appropriate conditions. Persisters underlie persistent and …

Intracellular bacterial pathogens can exhibit large heterogeneity in growth rate inside host
cells, with major consequences for the infection outcome. If and how the host responds to …