Recent insights into eukaryotic translation initiation factors 5A1 and 5A2 and their roles in human health and disease

GQ Wu, YM Xu, ATY Lau - Cancer Cell International, 2020 - Springer
The eukaryotic translation initiation factor 5A1 (eIF5A1) and its homolog eIF5A2 are the only
two human proteins containing the unique post-translational modification–hypusination …

Plasma miR-9-3p and miR-136-3p as potential novel diagnostic biomarkers for experimental and human mild traumatic brain injury

S Das Gupta, R Ciszek, M Heiskanen… - International journal of …, 2021 - mdpi.com
Noninvasive, affordable circulating biomarkers for difficult-to-diagnose mild traumatic brain
injury (mTBI) are an unmet medical need. Although blood microRNA (miRNA) levels are …

Discovery and validation of circulating microRNAs as biomarkers for epileptogenesis after experimental traumatic brain injury–the EPITARGET cohort

M Heiskanen, S Das Gupta, JD Mills… - International journal of …, 2023 - mdpi.com
Traumatic brain injury (TBI) causes 10–20% of structural epilepsies and 5% of all epilepsies.
The lack of prognostic biomarkers for post-traumatic epilepsy (PTE) is a major obstacle to …

[HTML][HTML] MicroRNA-434-3p regulates age-related apoptosis through eIF5A1 in the skeletal muscle

PS Pardo, A Hajira, AM Boriek, JS Mohamed - Aging (Albany NY), 2017 - ncbi.nlm.nih.gov
Increased activation of catabolic pathways, including apoptosis causes sarcopenia.
However, the precise molecular mechanism that initiates apoptosis during aging is not well …

Novel circular RNAs expressed in brain microvascular endothelial cells after oxygen-glucose deprivation/recovery

W Liu, C Jia, L Luo, HL Wang, XL Min… - Neural regeneration …, 2019 - journals.lww.com
Circular RNAs (circRNAs) are generated by head-to-tail splicing and are ubiquitously
expressed in all multicellular organisms. Their important biological functions are …

Key genes expressed in different stages of spinal cord ischemia/reperfusion injury

J Li, C Zan, P Xia, C Zheng, Z Qi, C Li… - Neural Regeneration …, 2016 - journals.lww.com
The temporal expression of microRNA after spinal cord ischemia/reperfusion injury is not yet
fully understood. In the present study, we established a model of spinal cord ischemia in …

Mechanism of microRNA regulating the progress of atherosclerosis in apoE-deficient mice

X Lou, D Wang, Z Gu, T Li, L Ren - Bioengineered, 2021 - Taylor & Francis
MicroRNAs play important roles in atherosclerogenesis and are important novel
pharmaceutic targets in atherosclerosis management. The whole spectrum of miRNAs …

Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5

D Filipova, M Henry, T Rotshteyn, A Brunn, M Carstov… - PLoS …, 2018 - journals.plos.org
In skeletal muscle the coordinated actions of two mechanically coupled Ca2+ channels—the
1, 4-dihydropyridine receptor (Cav1. 1) and the type 1 ryanodine receptor (RYR1)–underlie …

Deregulation of microRNA-193b affects the proliferation of liver cancer via myeloid cell leukemia-1

W Yin, Y Nie, L Chen, Q Wang, S Liu… - Oncology …, 2018 - spandidos-publications.com
Abstract Deregulation of microRNA (miR)‑193b has been revealed to be associated with the
proliferation of liver cells. However, the interaction between miR‑193b and their targets …

Association of a newly identified lncRNA LNC_000280 with the formation of acetylcholine receptor clusters in vitro

J Deng, S Wang, S Meng, Z Qi, X Gu, C Huang… - Biochemical and …, 2022 - Elsevier
Peripheral nerve injury (PNI) can disintegrate acetylcholine receptor (AChR) clusters in the
postsynaptic membrane. In our previous research, lncRNAs that were differentially …