Clinical trials have shown that hyperthermia (HT), ie an increase of tissue temperature to 39–
44° C, significantly enhance radiotherapy and chemotherapy effectiveness [1]. Driven by the …

Drug delivery to solid tumour involves multiple physiological, biochemical and biophysical
processes taking place across a wide range of length and time scales. The therapeutic …

The blood-brain barrier (BBB) limits the delivery of systemically administered drugs to the
brain. Methods to circumvent the BBB have been developed, but none are used in standard …

Computational models of acoustic wave propagation are frequently used in transcranial
ultrasound therapy, for example, to calculate the intracranial pressure field or to calculate …

A rapid method for calculating the nearfield pressure distribution generated by a rectangular
piston is derived for time-harmonic excitations. This rapid approach improves the numerical …

Numerical modeling of medical ultrasound has advanced tremendously in the past two
decades. This opens up a great number of opportunities for medical ultrasound and …

Analytical two-dimensional (2D) integral expressions are derived for fast calculations of time-
harmonic and transient near-field pressures generated by apodized rectangular pistons …

This article investigates the restoration of ultrasonic pulse-echo C-scan images by means of
deconvolution with a point spread function (PSF). The deconvolution concept from linear …

Computation of acoustic radiation from a baffled circular piston continues be an active area
of investigation, both as a canonical problem and because of numerous practical …

A 1.5 MHz prolate spheroidal therapeutic array with 128 circular elements was designed to
accommodate standard imaging arrays for ultrasonic image-guided hyperthermia. The …