Prognostic role of DNA damage response genes mutations and their association with the sensitivity of olaparib in prostate cancer patients

D Zhang, X Xu, Y Wei, X Chen, G Li, Z Lu… - Cancer …, 2022 - journals.sagepub.com
Objective Evidence shows that gene mutation is a significant proportion of genetic factors
associated with prostate cancer. The DNA damage response (DDR) is a signal cascade …

Genetic polymorphisms in the mismatch repair pathway (MMR) genes contribute to hematological and gastrointestinal toxicity in North Indian lung cancer patients …

S Singh, N Singh, S Sharma - Journal of Biochemical and …, 2022 - Wiley Online Library
The present study investigated the relationship between MLH1, MSH2, MSH3, and MSH6
polymorphisms and toxicity due to platinum‐based doublet chemotherapy for North Indian …

Precision medicine path at personalized medicine research center/endocrinology and metabolism research institute: A systematic review

N Sarhangi, S Nikfar, M Hasanzad… - Journal of Diabetes & …, 2021 - Springer
Background Precision medicine is an evolving predictive, early preventive, and treatment
method that takes into account human gene heterogeneity for each individual. Personalized …

Utjecaj proteina hMSH3 i interleukina-6 na pojavnost mikrosatelitne nestabilnosti i dvolančanih lomova DNA u sporadičnom karcinomu debelog crijeva

A Salar - 2024 - dr.nsk.hr
Mikrosatelitna nestabilnost tipa EMAST i MSI rezultat je neispravnog popravka krivo
sparenih baza (MMR). EMAST je povezan s premještanjem hMSH3 iz jezgre u citoplazmu …

Association of MLH1-93G> A polymorphisms toward lung cancer susceptibility and its association with clinical outcome in North Indian patients treated with platinum …

S Singh, N Singh, M Baranwal… - Journal of Cancer …, 2023 - journals.lww.com
Background: Lung cancer is one of the most prevalent and main causes of malignancy-
related deaths worldwide, especially in developed countries. Epidemiological studies have …

عبور از رویکرد نوین پزشکی فرد محور در مرکز تحقیقات پزشکی فردی پژوهشگاه علوم غدد و متابولیسم: مرور نظام مند

حسن زاد ماندانا, سرهنگی نگار, نیک فر شکوفه… - 2020‎ - sid.ir
مقدمه: پزشکی فرد محور یک رویکرد جدید و در حال ظهور در عرصه ی علوم پزشکی است که از مشخصات
ژنتیکی هر فرد همراه با اطلاعات بالینی در جهت هدایت تصمیمات مربوط به پیشگیری, تشخیص …