An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …

Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular,
reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and …

Social interaction plays an essential role in species survival for socialized animals. Previous
studies have shown that a lack of social interaction such as social isolation, especially in the …

Located in the midbrain, the inferior colliculus (IC) is the hub of the central auditory system.
Although the IC plays important roles in speech processing, sound localization, and other …

Exposure to adversity during early childhood and adolescence increases an individual's
vulnerability to developing substance use disorder. Despite the knowledge of this …

The self-organization of the brain matrix of serotonergic axons (fibers) remains an unsolved
problem in neuroscience. The regional densities of this matrix have major implications for …

Social isolation raises the risk for mood disorders associated with serotonergic disruption.
Yet, the underlying mechanisms by which the stress of social isolation increases risk are not …

Located in the midbrain, the inferior colliculus (IC) integrates information from numerous
auditory nuclei and is an important hub for sound processing. Despite its importance, little is …

The serotonergic system has been widely studied across animal taxa and different functional
networks. This modulatory system is therefore well positioned to compare the consequences …

For social animals that communicate acoustically, hearing loss and social isolation are
factors that independently influence social behavior. In human subjects, hearing loss may …