[HTML][HTML] Sulforaphane and its bifunctional analogs: Synthesis and biological activity

Ł Janczewski - Molecules, 2022 - mdpi.com
For decades, various plants have been studied as sources of biologically active compounds.
Compounds with anticancer and antimicrobial properties are the most frequently desired …

Chemistry routes for copolymer synthesis containing PEG for targeting, imaging, and drug delivery purposes

K Rahme, N Dagher - Pharmaceutics, 2019 - mdpi.com
Polyethylene glycol (PEG) is one of the most frequently used polymers for coating
nanocarriers to enhance their biocompatibility, hydrophilicity, stability, and biodegradability …

Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors

NM Saleh, MSA El-Gaby, K El‐Adl… - Bioorganic …, 2020 - Elsevier
Novel series of diazepam bearing sulfonamide moieties 5 af and 7 ac were designed,
synthesized and evaluated for anticancer activity against HepG2, HCT-116 and MCF-7 cell …

Supramolecular self-assembly of a coumarine-based acylthiourea synthon directed by π-stacking interactions: Crystal structure and Hirshfeld surface analysis

A Saeed, S Ashraf, U Flörke, ZYD Espinoza… - Journal of Molecular …, 2016 - Elsevier
Abstract The structure of 1-(2-oxo-2H-chromene-3-carbonyl)-3-(2-methoxy-phenyl) thiourea
(1) has been determined by single-crystal X-ray crystallography. This compound crystallizes …

Synthesis, characterization, computational study, and screening of novel 1-phenyl-4-(2-phenylacetyl)-thiosemicarbazide derivatives for their antioxidant and …

AA Altalhi, HE Hashem, NA Negm, EA Mohamed… - Journal of Molecular …, 2021 - Elsevier
Condensation reaction of phenyl acetyl isothiocyanate (1) and phenyl hydrazine was
performed to obtain 1-phenyl-4-(2-phenylacetyl) thiosemicarbazide (2). Compound (2) was …

Novel acyl thiourea derivatives: Synthesis, antifungal activity, gene toxicity, drug‐like and molecular docking screening

L Antypenko, F Meyer, O Kholodniak… - Archiv der …, 2019 - Wiley Online Library
Nine novel acyl thioureas were synthesized. Their identities and purities were confirmed by
LC‐MS spectra; each structure was elucidated by elemental analysis, IR, 1Н and 13C NMR …

Isothiocyanates in Brassica: Potential anti cancer agents

A Sharma, A Sharma, P Yadav… - Asian pacific Journal of …, 2016 - journal.waocp.org
Isothiocyanates are naturally occurring small molecules that are formed from glucosinolate
precursors of cruciferous vegetables. Many isothiocyanates, both natural and synthetic …

Biofumigation: Opportunities and challenges for control of soilborne diseases in nursery production

F Baysal-Gurel, P Liyanapathiranage… - Plant Health …, 2018 - Am Phytopath Society
Soilborne diseases reduce crop performance, increase costs to the nursery producers, and
can cause potential ecological damage to the natural environment. In particular, soilborne …

Utility of thiophene-2-carbonyl isothiocyanate as a precursor for the synthesis of 1, 2, 4-triazole, 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole derivatives with evaluation of …

IF Nassar, SR Att-Allah, MM Hemdan - Phosphorus, Sulfur, and …, 2018 - Taylor & Francis
The reaction of thiophene-2-carbonyl isothiocyanate with phenylhydrazine gave 1-phenyl-5-
(thien-2-yl)-1, 2, 4-triazole-3-thiol which was transformed by follow-up reactions into …

Dodecanoyl isothiocyanate and N′-(2-cyanoacetyl) dodecanehydrazide as precursors for the synthesis of different heterocyclic compounds with interesting …

MF Ismail, GA Elsayed - Synthetic Communications, 2018 - Taylor & Francis
Dodecanoyl isothiocyanate 1 was utilized for the construction of thioureido, 2-thioxo-2, 3-
dihydroquinazolin-4 (1 H)-one, benzo [d]-1, 3-thiazin-4 (H)-one and 3-amino quinazolin-4 (3 …