Abstract Proton Pump Inhibitors are used widely to manage many gastric acid-related
conditions such as gastroesophageal disease, gastritis, esophagitis, Barrett's esophagus …

Background Colorectal cancer which is related to genetic and environmental risk factors, is
among the most prevalent life-threatening cancers. Although several pathogenic bacteria …

Colorectal cancer (CRC) is a common malignancy of the gastrointestinal tract, accounting for
the second most common cause of gastrointestinal tumors. As one of the intestinal barriers …

The Hippo pathway is an evolutionarily conserved pathway that serves to promote cell death
and differentiation while inhibiting cellular proliferation across species. The downstream …

Objectives: Increasing evidence suggested that proton pump inhibitors (PPIs) use might
affect the development of cancers, but previous conclusions remain controversial. Therefore …

Gastroduodenal inflammation and ulcerative injuries are increasing due to expanding socio-
economic stress, unhealthy food habits-lifestyle, smoking, alcoholism and usage of …

Background The effects of proton-pump inhibitors (PPIs) on the infant microbiome remain
unclear. Swedish pilot cohort study to assess the longitudinal effect of long-term PPI on the …

Colorectal cancer (CRC) is one of the most common tumors worldwide, with a higher rate of
distant metastases than other malignancies and with regular occurrence of drug resistance …

Purpose The increased risk of colorectal cancer (CRC) associated with long-term use of
proton pump inhibitors (PPIs) has attracted considerable attention; however, the conclusions …

OBJECTIVE: Proton pump inhibitors (PPIs) are among the drugs most commonly used in
critically ill patients. Although mainly applied temporarily for stress ulcer prophylaxis, their …