Multi-dimensional liquid chromatography (MD-LC) continues to gain in popularity for
applications where conventional one-dimensional liquid chromatography is insufficient to …

Despite progress in hardware and column technology, the complexity and heterogeneity of
many samples still pose a challenge for state-of-the-art 1D liquid chromatography (LC). As …

Enantioselective chromatography has been the preferred technique for the determination of
enantiomeric excess across academia and industry. Although sequential multicolumn …

The (bio) pharmaceutical industry is rapidly moving towards complex drug modalities that
require a commensurate level of analytical enabling technologies that can be deployed at a …

Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

This work presents an advanced analytical platform for untargeted enantioselective amino
acid analysis (eAAA) by comprehensive achiral× chiral 2D-LC hyphenated to ESI-QTOF …

Recent developments in two-dimensional liquid chromatography (2D-LC) now make
separation and analysis of very complex mixtures achievable. Despite being such a …

At the forefront of chemistry and biology research, development timelines are fast‐paced
and large quantities of pure targets are rarely available. Herein, we introduce a new …

In this work, we present a unique, robust and fully automated analytical platform technology
for the enantioselective amino acid analysis using a multiple heart cutting RPLC-enantio …

Tandem column liquid chromatography (LC) is a convenient, cost-effective approach to
resolve multicomponent mixtures by serially coupling columns on readily available one …