Chronic exposure to elevated levels of manganese via occupational or environmental
settings causes a neurological disorder known as manganism, resembling the symptoms of …

Over the past decade, major discoveries in retrotransposon biology have depicted the
neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 …

Local, synaptic synthesis of new proteins in response to neuronal stimulation plays a key
role in the regulation of synaptic morphogenesis. Recent studies indicate that matrix …

In many psychiatric, neurodegenerative and systemic inflammatory disorders circadian
melatonin is decreased whilst melatonin enzymes and melatonin receptors are genetic …

Herein, we discuss data concerning the involvement of transcription factor Yin Yang 1 (YY1)
in the development of brain diseases, highlighting mechanisms of its pathological actions …

Rett syndrome is a severe neurodevelopmental disorder mainly caused by mutations in the
transcriptional regulator MeCP2. Although there is no effective therapy for Rett syndrome …

The highly conserved and ubiquitously expressed transcription factor Yin Yang 1 (Yy1), was
named after its dual functions of both activating and repressing gene transcription. Yy1 plays …

During the last decade, multiple data have been obtained, pointing to an involvement of
extracellular, including extrasynaptic, proteolysis in epilepsy pathogenesis. The most …

Abstract α-synuclein (SNCA) is an established susceptibility gene for Parkinson's disease
(PD), one of the most common human neurodegenerative disorders. Increased SNCA is …

Previously, we found that chronic methamphetamine treatment altered cannabinoid type 1
receptor (CB1R)‐dependent cAMP/PKA/dopamine and cAMP‐regulated phosphoprotein of …