The coronavirus disease (COVID-19) pandemic has placed a massive impact on global
civilization. Finding effective treatments and drugs for these viral diseases was crucial. This …

Opposing effects of interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) on SARS-
CoV-2 infection have been reported. The reasons for this are unclear and the role of IFITMs …

ABSTRACT COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) has had a devastating impact on global public health, emphasizing the …

During virus infection, many host proteins are redirected from their normal cellular roles to
restrict and terminate infection. Heterogeneous nuclear ribonucleoproteins (hnRNPs) are …

The infection of CD4 T-lymphocytes with human immunodeficiency virus (HIV), the
etiological agent of acquired immunodeficiency syndrome (AIDS), disrupts cellular …

The early steps of viral infection involve protein complexes and structural lipid
rearrangements which characterize the peculiar strategies of each virus to invade …

Influenza A viruses (IAV), significant respiratory pathogenic agents, cause seasonal
epidemics and global pandemics in intra-and interannual cycles. Despite effective therapies …

Invasive bacterial disease is a major burden on healthcare worldwide. In serious cases, it
can lead to lifelong morbidity or death. This thesis focuses on invasive diseases caused by …

Viruses are equipped with effective strategies to turn infected host cells into factories of virus
production. To achieve this, viruses interact with a myriad of mammalian host-cell …

Parvovirus B19 (B19V) is a ssDNA virus, with a 5596 nt long genome encapsidated within
an icosahedral capsid with a diameter of 22 nm. Viral proteins are subdivided into structural …