Regenerative therapies for spinal cord injury

N Ashammakhi, HJ Kim, A Ehsanipour… - … Engineering Part B …, 2019 - liebertpub.com
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

Recent advances in the fabrication, functionalization, and bioapplications of peptide hydrogels

Y Wang, W Zhang, C Gong, B Liu, Y Li, L Wang, Z Su… - Soft Matter, 2020 - pubs.rsc.org
Self-assembled peptide-based nanomaterials have exhibited wide application potential in
the fields of materials science, nanodevices, biomedicine, tissue engineering, biosensors …

Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury

S Kabu, Y Gao, BK Kwon, V Labhasetwar - Journal of Controlled Release, 2015 - Elsevier
Spinal cord injury (SCI) results in devastating neurological and pathological consequences,
causing major dysfunction to the motor, sensory, and autonomic systems. The primary …

[HTML][HTML] Peptide hydrogels–versatile matrices for 3D cell culture in cancer medicine

P Worthington, DJ Pochan, SA Langhans - Frontiers in oncology, 2015 - frontiersin.org
Traditional two-dimensional (2D) cell culture systems have contributed tremendously to our
understanding of cancer biology but have significant limitations in mimicking in vivo …

Biomaterial scaffolds in regenerative therapy of the central nervous system

Y Wang, H Tan, X Hui - BioMed research international, 2018 - Wiley Online Library
The central nervous system (CNS) is the most important section of the nervous system as it
regulates the function of various organs. Injury to the CNS causes impairment of …

Emerging role of injectable dipeptide hydrogels in biomedical applications

N Kulkarni, P Rao, GS Jadhav, B Kulkarni… - ACS …, 2023 - ACS Publications
Owing to their properties such as biocompatibility, tunable mechanical properties,
permeability toward oxygen, nutrients, and the ability to hold a significant amount of water …

Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus

H Kanno, DD Pearse, H Ozawa, E Itoi… - Reviews in the …, 2015 - degruyter.com
Abstract Transplantation of Schwann cells (SCs) is a promising therapeutic strategy for
spinal cord repair. The introduction of SCs into the injured spinal cord has been shown to …

Vascularization of self-assembled peptide scaffolds for spinal cord injury repair

KA Tran, PP Partyka, Y Jin, J Bouyer, I Fischer… - Acta Biomaterialia, 2020 - Elsevier
The disruption of the blood-spinal cord barrier (BSCB) following spinal cord injury
contributes to inflammation and glial scarring that inhibits axon growth and diminishes the …

[HTML][HTML] Hydrogels as scaffolds and delivery systems to enhance axonal regeneration after injuries

OA Carballo-Molina, I Velasco - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Damage caused to neural tissue by disease or injury frequently produces a discontinuity in
the nervous system (NS). Such damage generates diverse alterations that are commonly …

Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications

R Wang, Z Wang, Y Guo, H Li… - Journal of Biomaterials …, 2019 - Taylor & Francis
RADA16 (RADARADARADARADA) is an amphiphilic polypeptide composed of 16 amino
acids, which is composed of alternating positively charged arginine (R), hydrophobic …