The physiology of the preterm and term neonate is characterized by a high metabolic rate,
limited pulmonary, cardiac and thermoregulatory reserve, and decreased renal function …

The induction characteristics, dosage requirements, cardiovascular and respiratory effects of
propofol with added lignocaine were compared with those of thiopentone and halothane …

We studied the emergence characteristics of unpremedicated children tracheally extubated
while deeply anesthetized (" deep extubation") with isoflurane or sevoflurane. Forty children …

To better understand the mechanism of hypotension and bradycardia that may occur in
newborn infants during isoflurane anesthesia, we studied the hemodynamic changes in the …

The characteristics of induction with and recovery from isoflurane anaesthesia were studied
in 248 children. The mean time to loss of consciousness was 1.5 min (SD 0.5). Tracheal …

The uptake of halothane is known to be more rapid in children than in adults, but
comparable clinical data regarding other inhalational anaesthetics are not available. In this …

In this study, two-dimensional and pulsed Doppler echocardiography were used to measure
cardiovascular changes before and after IV atropine in 31 infants and small children during …

Background N-methyl-d-aspartate (NMDA) receptor antagonists are neuroprotective in
animal models of cerebral ischemia, but adverse cardiovascular and neurobehavioral …

Neonatal myocardium is distinctly more sensitive to extracellular calcium levels than is
mature myocardium. This has been ascribed to the poorly developed sarcoplasmic reticulum …

Congenital heart defects occur in approximately seven of every 1,000 births (70). The most
common of these are ventricular septal defects, patent ductus arteriosus, pulmonic stenosis …