[HTML][HTML] Microvascularized tumor organoids-on-chips: advancing preclinical drug screening with pathophysiological relevance

J Lim, H Ching, JK Yoon, NL Jeon, YT Kim - Nano Convergence, 2021 - Springer
Recent developments of organoids engineering and organ-on-a-chip microfluidic
technologies have enabled the recapitulation of the major functions and architectures of …

Advances in TEER measurements of biological barriers in microphysiological systems

H Nazari, J Shrestha, VY Naei, SR Bazaz… - Biosensors and …, 2023 - Elsevier
Biological barriers are multicellular structures that precisely regulate the transport of ions,
biomolecules, drugs, cells, and other organisms. Transendothelial/epithelial electrical …

Construction of a high fidelity epidermis-on-a-chip for scalable in vitro irritation evaluation

J Zhang, Z Chen, Y Zhang, X Wang, J Ouyang, J Zhu… - Lab on a Chip, 2021 - pubs.rsc.org
3D skin equivalents have been increasingly used in the pharmaceutical and cosmetic
industries, but the troublesome operation procedure and low throughput restricted their …

[HTML][HTML] Recent trends of biomaterials and biosensors for organ-on-chip platforms

IM Gonçalves, RO Rodrigues, AS Moita, T Hori, H Kaji… - Bioprinting, 2022 - Elsevier
Abstract Organ-on-chip (OoC) platforms are a new class of advanced microfluidic devices
that have been attracting significant attention for drug development since they can allow a …

[HTML][HTML] In vitro microvascular engineering approaches and strategies for interstitial tissue integration

AR Murphy, MC Allenby - Acta Biomaterialia, 2023 - Elsevier
The increasing gap between clinical demand for tissue or organ transplants and the
availability of donated tissue highlights the emerging opportunities for lab-grown or …

Models for barrier understanding in health and disease in lab-on-a-chips

J Ponmozhi, S Dhinakaran, D Kocsis, K Iván… - Tissue …, 2024 - Taylor & Francis
The maintenance of body homeostasis relies heavily on physiological barriers. Dysfunction
of these barriers can lead to various pathological processes, including increased exposure …

[HTML][HTML] Advances in the engineering of the outer blood-retina barrier: From in-vitro modelling to cellular therapy

C Dujardin, W Habeler, C Monville, D Letourneur… - Bioactive Materials, 2024 - Elsevier
The outer blood-retina barrier (oBRB), crucial for the survival and the proper functioning of
the overlying retinal layers, is disrupted in numerous diseases affecting the retina, leading to …

[HTML][HTML] Integrating mechanical sensor readouts into organ-on-a-chip platforms

IA Morales, CM Boghdady, BE Campbell… - … in Bioengineering and …, 2022 - frontiersin.org
Organs-on-a-chip have emerged as next-generation tissue engineered models to accurately
capture realistic human tissue behaviour, thereby addressing many of the challenges …

Combining ultrasound-mediated intracellular delivery with microfluidics in various applications

G Huang, L Lin, S Wu, H Dang, X Cheng, Y Liu, H You - BioChip Journal, 2024 - Springer
Ultrasound-mediated intracellular delivery is one of the popular technologies based on
membrane rupture at present. To date, ultrasound directly acts on a large number of cells to …

[HTML][HTML] Mimicking blood and lymphatic vasculatures using microfluidic systems

E Hall, K Mendiola, NK Lightsey, D Hanjaya-Putra - Biomicrofluidics, 2024 - pubs.aip.org
The role of the circulatory system, containing the blood and lymphatic vasculatures, within
the body, has become increasingly focused on by researchers as dysfunction of either of the …