Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitochondria are energy-producing organelles that not only satisfy the high metabolic
demands of the kidney but sense and respond to kidney injury-induced oxidative stress and …

Mitochondrial biology has seen a surge in popularity in the past 5 years, with the emergence
of numerous new avenues of exciting mitochondria-related research including …

Cell-free mitochondrial DNA (cf-mtDNA) is a marker of inflammatory disease and a predictor
of mortality, but little is known about cf-mtDNA in relation to psychobiology. A systematic …

Mitochondria are indispensable for energy metabolism and cell signaling. Mitochondrial
homeostasis is sustained with stabilization of mitochondrial membrane potential, balance of …

Background Aging is one of the key contributing factors for chronic obstructive pulmonary
diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how …

Cigarette smoke (CS) is the most common risk factor for chronic obstructive pulmonary
disease (COPD). The present study aimed to elucidate whether mtDNA is released upon CS …

Age is a major risk factor for chronic respiratory diseases such as idiopathic pulmonary
fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and certain phenotypes of …

Cigarette smoking impacts DNA methylation, but the investigation of sex-specific features of
lung tissue DNA methylation in smokers has been limited. Women appear more susceptible …

The past thirty years have seen a surge in interest in pathophysiological roles of
mitochondria, and the accurate quantification of mitochondrial DNA copy number (mCN) in …