The significant parallels between cell plasticity during embryonic development and
carcinoma progression have helped us understand the importance of the epithelial …

Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …

Accumulating evidences indicate that long noncoding RNAs (lncRNAs) might play important
roles in tumorigenesis and metastasis. EMT (epithelial-to-mesenchymal transition) is …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid malignancies
and is characterized by its insensitivity to current therapy. The invasion and metastasis of …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common human
malignancy in the world, with high mortality and poor prognosis for patients. Among the risk …

Master regulators of the epithelial-mesenchymal transition such as Twist1 and Snail1 have
been implicated in invasiveness and the generation of cancer stem cells, but their persistent …

HOX transcript antisense intergenic RNA (HOTAIR), a well-known long non-coding RNA,
plays an important role in the regulation of epithelial-to-mesenchymal transition (EMT). In …

Cancer is the second leading cause of death worldwide and disease burden is expected to
increase globally throughout the next several decades, with the majority of cancer-related …

Long non-coding RNAs (lncRNAs) are being discovered as a novel family of regulators of
gene expression at the epigenetic level. Emerging lines of evidence demonstrate that …

Epithelial to mesenchymal transition (EMT) is a central regulatory program that is similar in
many aspects to several steps of embryonic morphogenesis. In addition to its physiological …