Three prominent health challenges affecting our society include cancer, diabetes, and
antibiotic-resistant infections. Despite the availability of conventional drugs for these …

In the present study, 28 acyl hydrazones (4–31) of flurbiprofen were synthesized in good to
excellent yield by reacting different aromatic aldehydes with the commercially available drug …

Bis-Schiff's base derivatives of 4-nitroacetophenone (1–18) were synthesized in good yields
by reacting hydrazone of 4-nitroacetophenone with substituted aldehydes and ketones with …

α-Glucosidase is related to the increase in postprandial blood glucose in vivo. Inhibition of α-
glucosidase is supposed to be an effective approach to treat type 2 diabetes mellitus …

To develop novel α-glucosidase inhibitors, a series of chromone-based phenylhydrazone
and benzoylhydrazone derivatives were designed, synthesized, and evaluated their …

To find potential α-glucosidase inhibitors, indolo [1, 2-b] isoquinoline derivatives (1–20)
were screened for their α-glucosidase inhibitory effects. All derivatives presented potential α …

Tetracoordinated ONNO purine‐based novel Schiff base (1) and its metal complexes Co (II),
Ni (II), Cu (II), and Zn (II)(2–5) were procured from 2, 6‐diaminopurine and 5 …

In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …

A series of pyrazole-Schiff base derivatives, 3a-i, were synthesized by reacting arylamines
2a-i with pyrazole aldehyde 1, utilizing two catalysts: ammonium chloride (catalyst A) or …

Diabetes mellitus is one of the most prevalent diseases nowadays. Several marketed drugs
are available for the cure and treatment of diabetes, but there is still a dire need of …