Worldwide prevalence of mild cognitive impairment among community dwellers aged 50 years and older: a meta-analysis and systematic review of epidemiology …

W Bai, P Chen, H Cai, Q Zhang, Z Su, T Cheung… - Age and …, 2022 - academic.oup.com
Background Mild cognitive impairment (MCI) is the preclinical and transitional stage
between healthy ageing and dementia that may be a potential 'target'for interventions …

Neuroinflammatory markers: key indicators in the pathology of neurodegenerative diseases

A Rauf, H Badoni, T Abu-Izneid, A Olatunde… - Molecules, 2022 - mdpi.com
Neuroinflammation, a protective response of the central nervous system (CNS), is
associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of …

Global estimates on the number of persons across the Alzheimer's disease continuum

A Gustavsson, N Norton, T Fast, L Frölich… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Global estimates on numbers of persons in early stages of Alzheimer's disease
(AD), including prodromal and preclinical, are lacking, yet are needed to inform policy …

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life

KA Walker, J Chen, L Shi, Y Yang, M Fornage… - Science translational …, 2023 - science.org
A diverse set of biological processes have been implicated in the pathophysiology of
Alzheimer's disease (AD) and related dementias. However, there is limited understanding of …

Recent advancements in pathogenesis, diagnostics and treatment of Alzheimer's disease

S Khan, KH Barve, MS Kumar - Current neuropharmacology, 2020 - ingentaconnect.com
Background: The only conclusive way to diagnose Alzheimer's is to carry out brain autopsy
of the patient's brain tissue and ascertain whether the subject had Alzheimer's or any other …

The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease

M Amidfar, J de Oliveira, E Kucharska, J Budni, YK Kim - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

[HTML][HTML] Dementia epidemiology fact sheet 2022

JH Shin - Annals of Rehabilitation Medicine, 2022 - synapse.koreamed.org
This dementia epidemiology fact sheet 2022 is aimed at providing an overview of the
epidemiology of dementia in Korea using representative government-led data. This review …

Biomarkers for Alzheimer's disease: current status and prospects for the future

K Blennow, H Zetterberg - Journal of internal medicine, 2018 - Wiley Online Library
Accumulating data from the clinical research support that the core Alzheimer's disease (AD)
cerebrospinal fluid (CSF) biomarkers amyloid‐β (Aβ42), total tau (T‐tau), and …

Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the …

RC Petersen, O Lopez, MJ Armstrong, TSD Getchius… - Neurology, 2018 - AAN Enterprises
Objective To update the 2001 American Academy of Neurology (AAN) guideline on mild
cognitive impairment (MCI). Methods The guideline panel systematically reviewed MCI …

Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

L Vermunt, SAM Sikkes, A Van Den Hout… - Alzheimer's & …, 2019 - Elsevier
Introduction We estimated the age-specific duration of the preclinical, prodromal, and
dementia stages of Alzheimer's disease (AD) and the influence of sex, setting …