The ability of cells to extend cell membranes is central to numerous biological processes,
including cell migration, cadherin-mediated junction formation and phagocytosis. Much …

Enteropathogenic Yersinia are gram-negative bacterial species that translocate from the
lumen of the intestine and are able to grow within deep tissue sites. During the earliest …

The Yersinia pseudotuberculosis invasin protein promotes bacterial entry by binding to host
cell integrins with higher affinity than natural substrates such as fibronectin. The 2.3 …

Intimin-γ is an outer membrane protein of enterohemorrhagic Escherichia coli (EHEC) O157:
H7 that is required for the organism to adhere tightly to HEp-2 cells and to colonize …

Enteric bacteria possess multiple fimbriae, many of which play critical roles in attachment to
epithelial cell surfaces. SEF14 fimbriae are only found in Salmonella enterica serovar …

Four “one-bead one-compound”(OBOC) combinatorial libraries were designed, synthesized,
and screened against MDA-MB-231 breast cancer cells. A novel cyclic peptide 1 (LXY1) with …

Introduction: Integrin receptors for cell adhesion to the extracellular matrix have important
roles in all stages of cancer progression and metastasis. Since the integrin family was …

Pathogenic Yersinia have a pronounced tropism for lymphatic tissues and harbor a
virulence plasmid that encodes a type III secretion system, pTTSS, that transports Yops into …

The NH 2-terminal portion (putative ligand-binding domain) of α subunits contains 7
homologous repeats, the last 3 or 4 of which possess divalent cation binding sequences …

Many adenovirus serotypes enter cells by high-affinity binding to the coxsackievirus-
adenovirus receptor (CAR) and integrin-mediated internalization. In the present study, we …