Respiratory cilia are the driving force of the mucociliary escalator, working in conjunction
with secreted airway mucus to clear inhaled debris and pathogens from the conducting …

Streptococcus pneumoniae is an important pathogen causing invasive diseases such as
sepsis, meningitis, and pneumonia. The burden of disease is highest in the youngest and …

Streptococcus pneumoniae is a Gram-positive bacterial pathogen that colonizes the
mucosal surfaces of the host nasopharynx and upper airway. Through a combination of …

Ciliopathies are a collection of disorders related to cilia dysfunction. Cilia are specialized
organelles that project from the surface of most cells. Motile and primary (sensory) cilia are …

An inverse correlation between colonization of the human nasopharynx by Streptococcus
pneumoniae and Haemophilus influenzae, both common upper respiratory pathogens, has …

Streptococcus pneumoniae (the pneumoccus) is the leading cause of otitis media,
community-acquired pneumonia, and bacterial meningitis. The success of the …

The development of bacterial disease has been likened to a'molecular arms race', in which
the host tries to eliminate the bacteria, while the bacteria try to survive in the host. Although …

Aerobic growth of Streptococcus pneumoniae results in production of amounts of hydrogen
peroxide (H2O2) that may exceed 1 mM in the surrounding media. H2O2 production by S …

Streptococcus pneumoniae is an opportunistic pathogen responsible for widespread illness
and is a major global health issue for children, the elderly, and the immunocompromised …

Diseases caused by Streptococcus pneumoniae include pneumonia, septicaemia and
meningitis. All these are associated with high morbidity and mortality. The pneumococcus …