The cellular stress response corresponds to the molecular changes that a cell undergoes in
response to various environmental stimuli. It induces drastic changes in the regulation of …

Recent advances in understanding different RNAs and unique features of their biology have
revealed a wealth of information. However, approaches to identify small molecules that …

SARS-CoV-2 coronavirus is responsible for the Covid-19 pandemic. In the early phase of
infection, the single-strand positive RNA genome is translated into nonstructural proteins …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently
emerged as a human pathogen and is the causative agent of the COVID-19 pandemic. A …

Internal ribosome entry site (IRES) elements are cis-acting RNA regions that promote
internal initiation of protein synthesis using cap-independent mechanisms. However, distinct …

Hepatitis C virus (HCV) infections are associated with the risk of progression to fibrosis,
cirrhosis, and hepatocellular carcinoma. The HCV RNA genome is translated by an internal …

To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell
entrance. Since viral genomes do not encode any components of the protein biosynthesis …

The cellular levels and activities of ribosomes directly regulate gene expression during
numerous physiological processes. The mechanisms that globally repress translation are …

Viruses exploit the translation machinery of an infected cell to synthesize their proteins.
Therefore, viral mRNAs have to compete for ribosomes and translation factors with cellular …

The majority of eukaryotic proteins are N-terminally α-acetylated by N-terminal
acetyltransferases (NATs). Acetylation usually occurs co-translationally and defects have …