Health Benefits of Silybum marianum: Phytochemistry, Pharmacology, and Applications

X Wang, Z Zhang, SC Wu - Journal of agricultural and food …, 2020 - ACS Publications
Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been
widely used to treat various diseases, especially hepatic diseases. The seeds and fruits of …

The potential role of flavonoids in ameliorating diabetic cardiomyopathy via alleviation of cardiac oxidative stress, inflammation and apoptosis

FF Jubaidi, S Zainalabidin, IS Taib, ZA Hamid… - International journal of …, 2021 - mdpi.com
Diabetic cardiomyopathy is one of the major mortality risk factors among diabetic patients
worldwide. It has been established that most of the cardiac structural and functional …

Mechanistic insights into the pharmacological significance of silymarin

K Wadhwa, R Pahwa, M Kumar, S Kumar, PC Sharma… - Molecules, 2022 - mdpi.com
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

[HTML][HTML] Silymarin is an ally against insulin resistance: A review

K MacDonald-Ramos, L Michán, A Martínez-Ibarra… - Annals of hepatology, 2021 - Elsevier
Silymarin is obtained from the Milk thistle plant Silybum marianum and has been used over
the centuries to treat principally liver disease, although it has also been studied for its …

Formulation of nanomicelles to improve the solubility and the oral absorption of silymarin

V Piazzini, M D'Ambrosio, C Luceri, L Cinci, E Landucci… - Molecules, 2019 - mdpi.com
Two novel nanomicellar formulations were developed to improve the poor aqueous
solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and …

[HTML][HTML] A review of medicinal plants for the treatment of diabetes mellitus: The case of Indonesia

FH Arifah, AE Nugroho, A Rohman… - South African Journal of …, 2022 - Elsevier
Indonesia is rich in biodiversity and ethnic groups, including those that use traditional
medicine to treat diabetes mellitus (DM). Ethnopharmacological of antidiabetic medicinal …

[HTML][HTML] Targeting epigenetics in diabetic cardiomyopathy: Therapeutic potential of flavonoids

Y Zhou, W Suo, X Zhang, Y Yang, W Zhao, H Li… - Biomedicine & …, 2023 - Elsevier
The pathophysiological mechanisms of diabetic cardiomyopathy have been extensively
studied, but there is still a lack of effective prevention and treatment methods. The ability of …

Reduction of blood glucose by plant extracts and their use in the treatment of diabetes mellitus; discrepancies in effectiveness between animal and human studies

BL Furman, M Candasamy, SK Bhattamisra… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance The global problem of diabetes, together with the limited
access of large numbers of patients to conventional antidiabetic medicines, continues to …

Silymarin: Not just another antioxidant

FC Camini, DC Costa - Journal of basic and clinical physiology and …, 2020 - degruyter.com
Abstract Silymarin (Silybum marianum; SM), popularly known as milk thistle, is an extract
that has been used for many centuries to treat liver diseases. In recent years, several studies …

Role of oxidative stress in Peyronie's disease: biochemical evidence and experiences of treatment with antioxidants

G Paulis, G De Giorgio, L Paulis - International Journal of Molecular …, 2022 - mdpi.com
Background: Peyronie's disease (PD) is a chronic inflammatory condition affecting adult
males, involving the tunica albuginea of the corpora cavernosa of the penis. PD is frequently …