[HTML][HTML] HSF1 Inhibits Antitumor Immune Activity in Breast Cancer by Suppressing CCL5 to Block CD8+ T-cell Recruitment
C Jacobs, S Shah, WC Lu, H Ray, J Wang… - Cancer Research, 2024 - AACR
Abstract Heat shock factor 1 (HSF1) is a stress-responsive transcription factor that promotes
cancer cell malignancy. To provide a better understanding of the biological processes …
cancer cell malignancy. To provide a better understanding of the biological processes …
An increase in HSF1 expression directs human mammary epithelial cells toward a mesenchymal phenotype
Simple Summary Epithelial, compactly packed cells form a protective layer lining the
surfaces of organs and cavities throughout the body. They can lose their features and gain …
surfaces of organs and cavities throughout the body. They can lose their features and gain …
[HTML][HTML] GSDME has prognostic and immunotherapeutic significance in residual hepatocellular carcinoma after insufficient radiofrequency ablation
X Liang, Q Liu, S Zhu, Z Li, H Chen, Z Su - Translational Oncology, 2024 - Elsevier
Background Heat stress can induce programmed cell death (PCD). Pyroptosis is a
gasdermin-mediated PCD. This study hypothesized that insufficient radiofrequency ablation …
gasdermin-mediated PCD. This study hypothesized that insufficient radiofrequency ablation …
Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA. 5 sublineages
Y Li, S Qin, L Dong, Y Xiao, Y Zhang, Y Hou, S Qiao… - …, 2024 - thelancet.com
Background Omicron sub-variants breakthrough infections (BTIs) have led to millions of
coronavirus disease 2019 (COVID-19) cases worldwide. The acute-phase immune status is …
coronavirus disease 2019 (COVID-19) cases worldwide. The acute-phase immune status is …
[HTML][HTML] Integrating Single-Cell RNA-Seq and ATAC-Seq Analysis Reveals Uterine Cell Heterogeneity and Regulatory Networks Linked to Pimpled Eggs in Chickens
W Li, X Ma, X Li, X Zhang, Y Sun, C Ning… - International Journal of …, 2024 - mdpi.com
Pimpled eggs have defective shells, which severely impacts hatching rates and
transportation safety. In this study, we constructed single-cell resolution transcriptomic and …
transportation safety. In this study, we constructed single-cell resolution transcriptomic and …
Entamoeba histolytica: In Silico and In Vitro Oligomerization of EhHSTF5 Enhances Its Binding to the HSE of the EhPgp5 Gene Promoter
S Pérez-Mora, DG Pérez-Ishiwara… - International Journal of …, 2024 - mdpi.com
Throughout its lifecycle, Entamoeba histolytica encounters a variety of stressful conditions.
This parasite possesses Heat Shock Response Elements (HSEs) which are crucial for …
This parasite possesses Heat Shock Response Elements (HSEs) which are crucial for …
Ex Vivo Evaluation of Glutamine Treatment in Sepsis and Trauma in a Human Peripheral Blood Mononuclear Cells Model
E Briassouli, M Tzanoudaki, D Goukos, K Vardas… - Nutrients, 2023 - mdpi.com
We aimed to assess the lipopolysaccharide (LPS), or heat shock (HS) induction, and
glutamine-modulating effects on heat shock protein-90α (HSP90α) and cytokines in an ex …
glutamine-modulating effects on heat shock protein-90α (HSP90α) and cytokines in an ex …