Gut-liver axis: Pathophysiological concepts and clinical implications

H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

Cholangiocarcinoma

PJ Brindley, M Bachini, SI Ilyas, SA Khan… - Nature reviews Disease …, 2021 - nature.com
Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system,
which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

CPG Panel, A Berzigotti, E Tsochatzis, J Boursier… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma

CL Bowlus, L Arrivé, A Bergquist, M Deneau… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Recent advances in clinical practice: epidemiology of autoimmune liver diseases

PJ Trivedi, GM Hirschfield - Gut, 2021 - gut.bmj.com
Autoimmune liver diseases are chronic inflammatory hepatobiliary disorders that when
classically defined encompass three distinctive clinical presentations; primary biliary …

[HTML][HTML] Primary sclerosing cholangitis–a comprehensive review

TH Karlsen, T Folseraas, D Thorburn, M Vesterhus - Journal of hepatology, 2017 - Elsevier
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Guidelines on the management of abnormal liver blood tests

PN Newsome, R Cramb, SM Davison, JF Dillon… - Gut, 2018 - gut.bmj.com
These updated guidelines on the management of abnormal liver blood tests have been
commissioned by the Clinical Services and Standards Committee (CSSC) of the British …

[HTML][HTML] Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma

A Lapitz, M Azkargorta, P Milkiewicz, P Olaizola… - Journal of …, 2023 - Elsevier
Background & Aims Cholangiocarcinoma (CCA), heterogeneous biliary tumours with dismal
prognosis, lacks accurate early diagnostic methods especially important for individuals at …

Primary sclerosing cholangitis

JK Dyson, U Beuers, DEJ Jones, AW Lohse, M Hudson - The Lancet, 2018 - thelancet.com
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …