Biology and hemodynamics of aneurysm rupture
CA Chitwood, ED Shih, O Amili… - Neurosurgery …, 2022 - neurosurgery.theclinics.com
What leads to aneurysm rupture versus stabilization is a question that has perplexed
researchers for decades, the answer would unquestionably influence how aneurysms are …
researchers for decades, the answer would unquestionably influence how aneurysms are …
Peripheral macrophages in the development and progression of structural cerebrovascular pathologies
DC Lauzier, AI Srienc, AK Vellimana… - Journal of Cerebral …, 2024 - journals.sagepub.com
The human cerebrovascular system is responsible for maintaining neural function through
oxygenation, nutrient supply, filtration of toxins, and additional specialized tasks. While the …
oxygenation, nutrient supply, filtration of toxins, and additional specialized tasks. While the …
Profiling of circulating gene expression reveals molecular signatures associated with intracranial aneurysm rupture risk
Background Following detection, rupture risk assessment for intracranial aneurysms (IAs) is
critical. Towards molecular prognostics, we hypothesized that circulating blood RNA …
critical. Towards molecular prognostics, we hypothesized that circulating blood RNA …
Dysregulated genes and signaling pathways in the formation and rupture of intracranial aneurysm
Intracranial aneurysm (IA) has the potential to rupture. Despite scientific advances, we are
still not in a position to screen patients for IA and identify those at risk of rupture. It is critical …
still not in a position to screen patients for IA and identify those at risk of rupture. It is critical …
RNA expression signatures of intracranial aneurysm growth trajectory identified in circulating whole blood
After detection, identifying which intracranial aneurysms (IAs) will rupture is imperative. We
hypothesized that RNA expression in circulating blood reflects IA growth rate as a surrogate …
hypothesized that RNA expression in circulating blood reflects IA growth rate as a surrogate …
RNA sequencing data from human intracranial aneurysm tissue reveals a complex inflammatory environment associated with rupture
VM Tutino, HR Zebraski, H Rajabzadeh-Oghaz… - Molecular Diagnosis & …, 2021 - Springer
Background Intracranial aneurysm (IA) rupture leads to deadly subarachnoid hemorrhages.
However, the mechanisms leading to rupture remain poorly understood. Altered gene …
However, the mechanisms leading to rupture remain poorly understood. Altered gene …
Identification of a 14-gene prognostic signature for diffuse large B cell lymphoma (DLBCL)
P Feng, H Li, J Pei, Y Huang, G Li - Frontiers in Genetics, 2021 - frontiersin.org
Although immunotherapy is a potential strategy to resist cancers, due to the inadequate
acknowledge, this treatment is not always effective for diffuse large B cell lymphoma …
acknowledge, this treatment is not always effective for diffuse large B cell lymphoma …
Glypican-1 may be a plasma biomarker for predicting the rupture of small intracranial aneurysms.
C Wang, Y Han, X Li - Journal of Proteomics, 2024 - Elsevier
Currently, there are no effective methods for predicting the rupture of asymptomatic small
intracranial aneurysms (IA)(< 7 mm). In this study the aim was to identify early warning …
intracranial aneurysms (IA)(< 7 mm). In this study the aim was to identify early warning …
Vasospasm in pediatric subarachnoid hemorrhage
I Mavridis, ES Pyrgelis, E Agapiou… - CNS & Neurological …, 2024 - benthamdirect.com
Cerebral vasospasm (CV) is a common severe complication of subarachnoid hemorrhage
(SAH), a severe type of intracranial bleeding that is uncommon in children. The purpose of …
(SAH), a severe type of intracranial bleeding that is uncommon in children. The purpose of …
Molecular Basis of Cerebral Vasospasm: What Can We Learn from Transcriptome and Temporal Gene Expression Profiling in Intracranial Aneurysm?
Cerebral vasospasm (CV) is a significant complication following aneurysmal subarachnoid
hemorrhage (aSAH), and lacks a comprehensive molecular understanding. Given the …
hemorrhage (aSAH), and lacks a comprehensive molecular understanding. Given the …