The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

Objectives/Hypothesis To perform a systematic review of GJB2‐associated hearing loss to
describe genotype distributions and auditory phenotype. Data Sources 230 primary studies …

SETTING: A high proportion of individuals with multidrug-resistant tuberculosis (MDR-TB)
develop permanent hearing loss due to ototoxicity caused by injectable aminoglycosides …

Mutations in connexins are the most common causes of hearing impairment (HI) in many
populations. Our aim was to review the global burden of pathogenic and likely pathogenic …

Our study aimed to investigate GJB2 (connexin 26) and GJB6 (connexin 30) mutations
associated with non-syndromic childhood hearing impairment (HI) as well as the …

The incidence of hearing impairment (HI) is higher in low-and middle-income countries
when compared to high-income countries. There is therefore a necessity to estimate the …

The rapid increase in genomics research in Africa and the growing promise of precision
public health (PPH) begs the question of whether African genomics has come of age and is …

Simple Summary The prevalence of GJB2-related (MIM: 121011) congenital non-syndromic
hearing impairment (NSHI) accounts for close to 50% in populations of Asian and European …

Background Genetic variations, including mitochondrial mutations, are important
contributors to hearing loss, especially in children, and newborn genetic screens for hearing …

Hearing impairment (HI) is highly heterogeneous with over 123 associated genes reported
to date, mostly from studies among Europeans and Asians. Here, we performed a systematic …