Sarcopenic obesity (SO) is a condition characterized by the occurrence of both sarcopenia
and obesity and imposes a heavy burden on the health of the elderly. Controversies and …

The heavy impact of obesity on both the population general health and the economy makes
clarifying the underlying mechanisms, identifying pharmacological targets, and developing …

Diverse pathologies (inflammation, tissues injuries, cancer, etc.) and physiological
conditions (obesity, physical activity, etc.) induce the expression/secretion of the …

In modern societies, ageing and obesity represent medical challenges for healthcare
professionals and caregivers. Obesity and ageing share common features including the …

Background and aims Non‐alcoholic fatty liver (NAFLD) and its more serious form non‐
alcoholic steatohepatitis increase risk of hepatocellular carcinoma (HCC). Lipid metabolic …

Secreted protein acidic and rich in cysteine (SPARC) is an extracellular matrix glycoprotein
with pleiotropic functions, which is expressed in adipose, hepatic, muscular, and pancreatic …

Abstract Three-dimensional (3D)-printed orthopedic surgical guides have the potential to
provide personalized precision treatment. Non-isocyanate polyurethane (NIPU) is commonly …

Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein
implicated in various functions, including metabolism, tissue regeneration, and functional …

Obesity represents a health problem resulting from a broken balance between energy intake
and energy expenditure leading to excess fat accumulation. Elucidating molecular and …

Extracellular matrix (ECM) remodeling plays important roles in both white adipose tissue
(WAT) and the skeletal muscle (SM) metabolism. Excessive adipocyte hypertrophy causes …