Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

High cholesterol/low cholesterol: effects in biological membranes: a review

WK Subczynski, M Pasenkiewicz-Gierula… - Cell biochemistry and …, 2017 - Springer
Lipid composition determines membrane properties, and cholesterol plays a major role in
this determination as it regulates membrane fluidity and permeability, as well as induces the …

Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research

EA Ainsbury, S Barnard, S Bright, C Dalke… - … Research/Reviews in …, 2016 - Elsevier
The lens of the eye has long been considered as a radiosensitive tissue, but recent research
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …

Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?

T Róg, I Vattulainen - Chemistry and physics of lipids, 2014 - Elsevier
Lipids rafts are considered to be functional nanoscale membrane domains enriched in
cholesterol and sphingolipids, characteristic in particular of the external leaflet of cell …

Insights into the biochemical and biophysical mechanisms mediating the longevity of the transparent optics of the eye lens

RA Quinlan, JI Clark - Journal of Biological Chemistry, 2022 - ASBMB
In the human eye, a transparent cornea and lens combine to form the" refracton" to focus
images on the retina. This requires the refracton to have a high refractive index" n," mediated …

Giant unilamellar vesicle electroformation: what to use, what to avoid, and how to quantify the results

Z Boban, I Mardešić, WK Subczynski, M Raguz - Membranes, 2021 - mdpi.com
Since its inception more than thirty years ago, electroformation has become the most
commonly used method for growing giant unilamellar vesicles (GUVs). Although the method …

Membrane models and experiments suitable for studies of the cholesterol bilayer domains

I Mardešić, Z Boban, WK Subczynski, M Raguz - Membranes, 2023 - mdpi.com
Cholesterol (Chol) is an essential component of animal cell membranes and is most
abundant in plasma membranes (PMs) where its concentration typically ranges from 10 to …

The eye in forensic medicine: a narrative review

JL Ang, SA Collis, B Dhillon… - The Asia-Pacific Journal of …, 2021 - journals.lww.com
The eye, with its distinctive anatomy, not only reflects a wide variety of diseases in life but
also undergoes a myriad of post-mortem changes. Consequently, the eye has long been an …

Permeability and microstructure of cholesterol-depleted skin lipid membranes and human stratum corneum

M Sochorová, P Audrlická, M Červená… - Journal of colloid and …, 2019 - Elsevier
Cholesterol (Chol) is one of the major skin barrier lipids. The physiological level of Chol in
the stratum corneum (SC) appears to exceed its miscibility with other barrier lipids, as some …

Binding of βL-Crystallin with Models of Animal and Human Eye Lens-Lipid Membrane

P Hazen, G Trossi-Torres, NK Khadka… - International Journal of …, 2023 - mdpi.com
Several discoveries show that with age and cataract formation, β-crystallin binds with the
lens membrane or associates with other lens proteins, which bind with the fiber cell plasma …