Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review
Objective To assess the methodological quality of studies on prediction models developed
using machine learning techniques across all medical specialties. Design Systematic …
using machine learning techniques across all medical specialties. Design Systematic …
[HTML][HTML] Early social adversity, altered brain functional connectivity, and mental health
Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …
factors for the onset of severe mental disorders and strong and consistent predictors of …
Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype?
Over the last years, the decreased costs and enhanced accessibility to large genome-wide
association studies datasets have laid the foundations for the development of polygenic risk …
association studies datasets have laid the foundations for the development of polygenic risk …
[HTML][HTML] Gender differences in the association between environment and psychosis
Various environmental exposures have been associated with psychosis spectrum disorder.
However, the role of gender in this association has received little attention. Therefore, we …
However, the role of gender in this association has received little attention. Therefore, we …
Association of preceding psychosis risk states and non‐psychotic mental disorders with incidence of clinical psychosis in the general population: A prospective study …
The validity and clinical utility of the concept of “clinical high risk”(CHR) for psychosis have
so far been investigated only in risk‐enriched samples in clinical settings. In this population …
so far been investigated only in risk‐enriched samples in clinical settings. In this population …
Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease
JA Hollander, DA Cory-Slechta, FN Jacka… - …, 2020 - nature.com
The etiologic pathways leading to neuropsychiatric diseases remain poorly defined. As
genomic technologies have advanced over the past several decades, considerable …
genomic technologies have advanced over the past several decades, considerable …
Need for ethnic and population diversity in psychosis research
C Burkhard, S Cicek, R Barzilay… - Schizophrenia …, 2021 - academic.oup.com
This article aims to evaluate “racial”, ethnic, and population diversity—or lack thereof—in
psychosis research, with a particular focus on socio-environmental studies. Samples of …
psychosis research, with a particular focus on socio-environmental studies. Samples of …
Factors moderating the association between cannabis use and psychosis risk: a systematic review
SJ Van der Steur, A Batalla, MG Bossong - Brain sciences, 2020 - mdpi.com
Increasing evidence indicates a relationship between cannabis use and psychosis risk.
Specific factors, such as determinants of cannabis use or the genetic profile of cannabis …
Specific factors, such as determinants of cannabis use or the genetic profile of cannabis …
Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum
AimsPsychosis spectrum disorder has a complex pathoetiology characterised by interacting
environmental and genetic vulnerabilities. The present study aims to investigate the role of …
environmental and genetic vulnerabilities. The present study aims to investigate the role of …
Association of recent stressful life events with mental and physical health in the context of genomic and exposomic liability for schizophrenia
Importance Both adulthood stressful life events (SLEs) and liability for schizophrenia have
been associated with poor mental and physical health in the general population, but their …
been associated with poor mental and physical health in the general population, but their …