The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …

Adipose tissue exhibits a remarkable capacity to expand, contract, and remodel in response
to changes in physiological and environmental conditions. Here, we describe recent …

Defects in adipocyte lipolysis drive multiple aspects of cardiometabolic disease, but the
transcriptional framework controlling this process has not been established. To address this …

Single-cell and single-nucleus RNA-sequencing (sxRNA-seq) is increasingly being used to
characterise the transcriptomic state of cell types at homeostasis, during development and in …

Obesity is a major driving factor in the incidence, progression, and poor treatment response
in gastrointestinal cancers. Herein, we conducted a comprehensive analysis of the impact of …

Technologies are transforming the understanding of adipose tissue as a complex and
dynamic tissue that plays a critical role in energy homoeostasis and metabolic health. This …

Simple Summary Progress in adipose research has shifted our understanding of adipose
tissue from being a homogenous, quiescent depot for energy storage to a highly dynamic …

Adipose tissue is a crucial organ in energy metabolism and thermoregulation. Adipose
tissue phenotype is controlled by various signaling mechanisms under pathophysiological …

The complexity of the tumor microenvironment poses significant challenges in cancer
therapy. Here, to comprehensively investigate the tumor-normal ecosystems, we perform an …