The multiple faces of C-reactive protein—physiological and pathophysiological implications in cardiovascular disease

M Boncler, Y Wu, C Watala - Molecules, 2019 - mdpi.com
C-reactive protein (CRP) is an intriguing protein which plays a variety of roles in either
physiological or pathophysiological states. For years it has been regarded merely as a …

Emerging biomarkers for the detection of cardiovascular diseases

S Thupakula, SSR Nimmala, H Ravula… - The Egyptian Heart …, 2022 - Springer
Background The prevalence of cardiovascular disease (CVD) has been continuously
increasing, and this trend is projected to continue. CVD is rapidly becoming a significant …

C-reactive protein as a prognostic factor in intensive care admissions for sepsis: A Swedish multicenter study

H Koozi, M Lengquist, A Frigyesi - Journal of critical care, 2020 - Elsevier
Purpose C-reactive protein (CRP) is not included in the major intensive care unit (ICU)
prognostic tools such as the Simplified Acute Physiology Score (SAPS). We assessed CRP …

C-reactive protein (CRP) measurement in geriatric patients hospitalized for acute infection

A Ticinesi, F Lauretani, A Nouvenne, E Porro… - European Journal of …, 2017 - Elsevier
The physiology of inflammatory response is modified by the aging process and is
substantially affected by multimorbidity and disability. Infection is the most frequent cause of …

3D‐Printed Hollow Microneedle‐Lateral Flow Devices for Rapid Blood‐Free Detection of C‐Reactive Protein and Procalcitonin

JG Turner, E Lay, U Jungwirth… - Advanced Materials …, 2023 - Wiley Online Library
Hollow microneedle devices as a technology for interstitial fluid extraction show promise for
the minimally invasive point‐of‐care detection of analytes. Despite increasing efforts toward …

Diagnostic and prognostic value of presepsin vs. established biomarkers in critically ill patients with sepsis or systemic inflammatory response syndrome

H Brodska, J Valenta, K Pelinkova, Z Stach… - Clinical Chemistry and …, 2018 - degruyter.com
Background: Inflammatory biomarkers may aid to distinguish between systemic inflammatory
response syndrome (SIRS) vs. sepsis. We tested the hypotheses that (1) presepsin, a novel …

A two-biomarker model predicts mortality in the critically ill with sepsis

C Mikacenic, BL Price, S Harju-Baker… - American journal of …, 2017 - atsjournals.org
Rationale: Improving the prospective identification of patients with systemic inflammatory
response syndrome (SIRS) and sepsis at low risk for organ dysfunction and death is a major …

[HTML][HTML] Neutrophil-to-lymphocyte ratio as a predictive marker for severe pediatric sepsis

X Zhong, A Ma, Z Zhang, Y Liu, G Liang - Translational Pediatrics, 2021 - ncbi.nlm.nih.gov
Background Although neutrophil-to-lymphocyte ratio (NLR) has been extensively studied in
several diseases, its role in pediatric sepsis remains unclear. Our study aimed to assess the …

Biomarkers for the Prediction and Judgement of Sepsis and Sepsis Complications: A Step towards precision medicine?

T Von Groote, M Meersch-Dini - Journal of Clinical Medicine, 2022 - mdpi.com
Sepsis and septic shock are a major public health concern and are still associated with high
rates of morbidity and mortality. Whilst there is growing understanding of different …

[HTML][HTML] High-sensitivity C-reactive protein/albumin ratio as a predictor of in-hospital mortality in older adults admitted to the emergency department

J Oh, SH Kim, KN Park, SH Oh, YM Kim… - Clinical and …, 2017 - ncbi.nlm.nih.gov
Objective The objective of this study was to test the hypothesis that an elevated high-
sensitivity C-reactive protein (hs-CRP)/albumin ratio at admission increases the risk of …