The PRECIS-2 tool: designing trials that are fit for purpose
PRECIS is a tool to help trialists make design decisions consistent with the intended
purpose of their trial. This paper gives guidance on how to use an improved, validated …
purpose of their trial. This paper gives guidance on how to use an improved, validated …
Effectiveness of centre‐based childcare interventions in increasing child physical activity: a systematic review and meta‐analysis for policymakers and practitioners
Context The review describes the effectiveness of physical activity interventions
implemented in centre‐based childcare services and (i) examines characteristics of …
implemented in centre‐based childcare services and (i) examines characteristics of …
Qualitative approaches to use of the RE-AIM framework: rationale and methods
Background There have been over 430 publications using the RE-AIM model for planning
and evaluation of health programs and policies, as well as numerous applications of the …
and evaluation of health programs and policies, as well as numerous applications of the …
Trends in the explanatory or pragmatic nature of cardiovascular clinical trials over 2 decades
N Sepehrvand, W Alemayehu, D Das, AK Gupta… - JAMA …, 2019 - jamanetwork.com
Importance Pragmatic trials test interventions using designs that produce results that may be
more applicable to the population in which the intervention will be eventually applied …
more applicable to the population in which the intervention will be eventually applied …
A framework for enhancing the value of research for dissemination and implementation
G Neta, RE Glasgow, CR Carpenter… - … journal of public …, 2015 - ajph.aphapublications.org
A comprehensive guide that identifies critical evaluation and reporting elements necessary
to move research into practice is needed. We propose a framework that highlights the …
to move research into practice is needed. We propose a framework that highlights the …
A pragmatic clinical trial examining the impact of a resilience program on college student mental health
Background One in three college students experience significant depression or anxiety
interfering with daily functioning. Resilience programs that can be administered to all …
interfering with daily functioning. Resilience programs that can be administered to all …
How pragmatic is it? Lessons learned using PRECIS and RE-AIM for determining pragmatic characteristics of research
B Gaglio, SM Phillips, S Heurtin-Roberts… - Implementation …, 2014 - Springer
Background The need for high-quality evidence that is applicable in real-world, routine
settings continues to increase. Pragmatic trials are designed to evaluate the effectiveness of …
settings continues to increase. Pragmatic trials are designed to evaluate the effectiveness of …
Efficacy and effectiveness trials have different goals, use different tools, and generate different messages
F Porzsolt, NG Rocha, AC Toledo-Arruda… - Pragmatic and …, 2015 - Taylor & Francis
The discussion about the optimal design of clinical trials reflects the perspectives of theory-
based scientists and practice-based clinicians. Scientists compare the theory with published …
based scientists and practice-based clinicians. Scientists compare the theory with published …
Heterogeneity in pragmatic randomised trials: sources and management
B Giraudeau, A Caille, SM Eldridge, C Weijer… - BMC medicine, 2022 - Springer
Background Pragmatic trials aim to generate evidence to directly inform patient, caregiver
and health-system manager policies and decisions. Heterogeneity in patient characteristics …
and health-system manager policies and decisions. Heterogeneity in patient characteristics …
Comparison of HIV screening strategies in the emergency department: a randomized clinical trial
JS Haukoos, MS Lyons, RE Rothman… - JAMA Network …, 2021 - jamanetwork.com
Importance The National HIV Strategic Plan for the US recommends HIV screening in
emergency departments (EDs). The most effective approach to ED-based HIV screening …
emergency departments (EDs). The most effective approach to ED-based HIV screening …